Results 51 to 60 of about 469,727 (312)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Isoperimetric inequalities for -Hessian equations
Advances in Nonlinear Analysis, 2012 We consider the homogeneous Dirichlet problem for a special -Hessian equation of sub-linear type in a -convex domain , . We study the comparison between the solution of this problem and the (radial) solution of the corresponding problem in a ball having ...
Mohammed Ahmed +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Shenzhen Daxue xuebao. Ligong banTo investigate the distribution law of non-limit state seismic passive earth pressure in a finite soil mass under the translational (T-mode) pattern of a rigid retaining wall, and to overcome the limitations of existing seismic earth pressure models that
ZHOU Tong +4 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Yantu gongcheng xuebao, 2018 Based on the unified solution of shear strength for unsaturated soils, a unified solution of Meyerhof’s ultimate bearing capacity for strip foundation is obtained by considering the effects of intermediate principal stress, matric suction and strength ...
ZHANG Chang-guang 1,2, YAN Qing 1, WU Li-zhou 2, CAO Xue-ye 1, ZHANG Cheng-lin 1
doaj +1 more source
gdpc: An R Package for Generalized Dynamic Principal Components
Journal of Statistical Software, 2020 gdpc is an R package for the computation of the generalized dynamic principal components proposed in Peña and Yohai (2016). In this paper, we briefly introduce the problem of dynamical principal components, propose a solution based on a reconstruction ...
Daniel Peña +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Bilevel optimisation as a solution method for an agri-environmental principal-agent problem
, 2019 The Modelling and Simulation Society of Australia and New Zealand Inc. All rights reserved. Recent computational advances in environmental modelling have enabled modellers to predict the impacts of spatially distributed management practices on ...
Barnhart, BL +4 more
core +1 more source