Results 51 to 60 of about 165,959,854 (300)

Relativity [PDF]

open access: yes, 2004
A brief review (~8K words) of the history and philosophy of special and general relativity for a Dictionary of the History of ...
Janssen, Michel
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Relativity without tears [PDF]

open access: yes, 2008
Special relativity is no longer a new revolutionary theory but a firmly established cornerstone of modern physics. The teaching of special relativity, however, still follows its presentation as it unfolded historically, trying to convince the audience of
Silagadze, Zurab
core  

Relatividades no ensino médio: o debate em sala de aula

open access: yesRevista Brasileira de Ensino de Física
A impossibilidade de detecção experimental do movimento uniforme absoluto, também conhecida como princípio da relatividade, não tem sido suficientemente abordada nas aulas de física do ensino médio.
Ricardo Avelar Sotomaior Karam   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

How Hume and Mach Helped Einstein Find Special Relativity [PDF]

open access: yes, 2004
In recounting his discovery of special relativity, Einstein recalled a debt to the philosophical writings of Hume and Mach. I review the path Einstein took to special relativity and urge that, at a critical juncture, he was aided decisively not by any ...
John D. Norton   +2 more
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Matter or geometry as fundamental in relativity theory: How not to teach special relativity [PDF]

open access: yes, 2013
In this paper, I review a number of interpretational frameworks for relativistic phenomena like length contraction and relativity of simultaneity. Of central focus is the book Physical Relativity by Harvey Brown, where Brown advocates a view in which ...
Hoving, Darryl G.
core  

The Geometrical Trinity of Gravity

open access: yesUniverse, 2019
The geometrical nature of gravity emerges from the universality dictated by the equivalence principle. In the usual formulation of General Relativity, the geometrisation of the gravitational interaction is performed in terms of the spacetime curvature ...
Jose Beltrán Jiménez   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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