Results 111 to 120 of about 11,855 (230)

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

What is Collaborative Care? Reexamining the Principles of Collaborative Care Through Scaling to Complex Populations and Settings. [PDF]

J Gen Intern Med
Hindmarch GM, Dopp AR, Mendon-Plasek SJ, Watkins KE.   +3 more
europepmc   +1 more source

Anode‐Free Sodium Metal Batteries: From Materials Design to System‐Level Integration

Advanced Science, EarlyView.
Anode‐free sodium metal batteries hold no sodium reserve, so every inefficiency becomes permanent loss. Resolving the inventory into reversible, dead, and chemically bound fractions exposes what Coulombic efficiency hides. Practical 500‐cycle operation requires above 99.95%, a threshold few systems meet under lean electrolyte and high areal capacity ...
Hamid Hussain, Shazaib Ali, Muhammad Ali, Samia Aman, Moazzam Ali, Ufra Naseer, Sajid Farooq, Asif Mahmood, Sailing He, Yinzhu Jiang, Muhammad Yousaf   +10 more
wiley   +1 more source

Study protocol for a target trial emulation: CHoosing the right diAlysis Modality in clinical PractIce: hemOdiafiltratioN or hemodialysis (CHAMPION). [PDF]

BMC Nephrol
Roos S, Larkin J, Ficociello LH, Usvyat LA, Jiao Y, Neri L, Zhou V, Brandjes M, Blankestijn PJ, Bots ML, Haitjema S, Verhaar MC, Janse RJ, Vernooij RWM.   +13 more
europepmc   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Comparison of GRACE, HEART, and TIMI Risk Scores in Predicting In-Hospital Morbidity and Mortality in Acute Coronary Syndrome. [PDF]

Cureus
Shaikh K, Sarfaraz A, Batool N, Sikandar F, Saher S, Kaleem F.   +5 more
europepmc   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

Advanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang, Xin Li, Ying Xiong, Xin Wang, Ying‐Wei Yang   +4 more
wiley   +1 more source

Longitudinal Psychosocial and Sleep Assessments for Long-Term Cardiovascular Risk Stratification after First Myocardial Infarction in Rural India. [PDF]

Med Princ Pract
Bhargava Sai M, Rai B, Dey D, Javvaji SK, Iyer VR, Kambhampati NSV, Ramamurthy SS, Rege G, Haloi N, Ganesh KM, D M.   +10 more
europepmc   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source

A novel interval prediction method with adaptive calibration for ship energy consumption prediction. [PDF]

Sci Rep
Hu Z, Li J, Zhou T, Zhang K, Xu S, Song X, Guo Y, Li S.   +7 more
europepmc   +1 more source