Background Hepatic resection is currently still the best choice of therapeutic strategies for liver cancer, but the long-term survival rate after surgery is unsatisfactory. Most patients develop intra- and/or extrahepatic recurrence. The reasons for this
Kuansheng Ma +11 more
core +2 more sources
Protective effect of propofol compared with sevoflurane on liver function after hepatectomy with Pringle maneuver: A randomized clinical trial. [PDF]
While the Pringle maneuver reduces intraoperative blood loss in hepatectomies, this technique can also be hepatotoxic. Hepatectomies require general anesthesia with propofol or volatile anesthetics like sevoflurane, agents known to offer multi-organ ...
Matsumi J, Sato T.
europepmc +3 more sources
Effects of a Pringle maneuver on jejunal mucosal oxygenation and blood flow in a porcine model. [PDF]
The Pringle maneuver is routinely used during hepatic surgery to reduce blood loss. However, its hemodynamic effects on extrahepatic organs—especially the gut—remain poorly understood.
Sartori S +8 more
europepmc +2 more sources
Background: The aim of this study was to compare postoperative outcomes following liver resection between patients with prolonged cumulative ischemia time (CIT) which exceeded 60 min and patients with CIT less than 60 min. Methods: Between March 2020 and
Predrag Zdujic +6 more
core +2 more sources
Selective Hepatic Vascular Exclusion versus Pringle Maneuver in Major Hepatectomy: A Systematic Review and Meta-Analysis. [PDF]
ObjectivesMortality and morbidity following hepatic resection is significantly affected by major intra-operative blood loss. This systematic review and meta-analysis evaluates whether selective hepatic vascular exclusion (SHVE) compared to a Pringle ...
Mobarak S +6 more
europepmc +2 more sources
A convenient and self-adjustable laparoscopic intracorporeal pringle maneuver using He's belt. [PDF]
Purpose This study introduces an intracorporeal Pringle maneuver (PM) using He’s belt for laparoscopic hepatectomy. Methods He’s belt, a silicone belt featuring a hole in the tail and eight cogs in the body, was placed in the abdominal cavity.
Zeng H +12 more
europepmc +2 more sources
Meta-analysis of the effect of the pringle maneuver on long-term oncological outcomes following liver resection. [PDF]
Hepatic pedicle clamping reduces intraoperative blood loss and the need for transfusion, but its long-term effect on survival and recurrence remains controversial.
Khajeh E +11 more
europepmc +2 more sources
Effect of intermittent Pringle maneuver on perioperative outcomes and long-term survival following liver resection in patients with hepatocellular carcinoma: a meta-analysis and systemic review. [PDF]
Background Intermittent Pringle maneuver (IPM) is commonly used to control bleeding during liver resection. IPM can cause ischemia–reperfusion injury, which may affect the prognosis of patients with hepatocellular carcinoma (HCC).
Hu L, Wang A, Qiao Y, Huang X.
europepmc +2 more sources
Changes in remimazolam plasma concentration associated with the Pringle maneuver during hepatectomy: a pilot study. [PDF]
Background Remimazolam (RMZ) is an ultrashort-acting benzodiazepine used in general anesthesia, metabolized rapidly by carboxylesterase 1, an enzyme primarily located in the liver.
Ogawa S +6 more
europepmc +2 more sources
Background Several techniques have been developed to reduce blood loss in liver resection. The half-Pringle and Pringle maneuvers are commonly used for inflow control.
Hao-Ping Wang +3 more
doaj +1 more source

