Results 111 to 120 of about 5,321,541 (286)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Exemplary teachers' approaches to supporting vocabulary development during shared reading [PDF]

open access: yes, 2014
An analysis of recent PIRLS (Progress in International Reading Literacy Study) data has shown that a group of New Zealand children are struggling to learn to read well.
Oliver, John-Paul
core  

The role of the home literacy environment in the early literacy development of children at family-risk of dyslexia [PDF]

open access: yes, 2013
This thesis examines the role of early home literacy environment (HLE) in the literacy development of a sample of children at family-risk of dyslexia via an affected first-degree relative (FR) and a typically developing control group (TD).
Hamilton, Lorna
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Vertical and horizontal reading training in patients with hemianopia and its effect on reading eye movements

open access: yesScientific Reports
Vertical reading training (VRTr) increases reading speed (RS) significantly in patients with hemianopic field defects (HFD). We ask, how eye movements (EM) contribute to this improvement and whether EM-behavior is affected by the side of HFD.
S. Kuester-Gruber   +5 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Modelling individual differences in reading using an optimised MikeNet simulator: the impact of reading instruction

open access: yesFrontiers in Human Neuroscience
Reading is vital for acquiring knowledge and studies have demonstrated that phonology-focused interventions generally yield greater improvements than meaning-focused interventions in English among children with reading disabilities.
Ya-Ning Chang   +5 more
doaj   +1 more source

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