Results 71 to 80 of about 5,321,541 (286)

Comparing Comprehension of a Long Text Read in Print Book and on Kindle: Where in the Text and When in the Story?

Frontiers in Psychology, 2019
Digital reading devices such as Kindle differ from paper books with respect to the kinesthetic and tactile feedback provided to the reader, but the role of these features in reading is rarely studied empirically.
Anne Mangen, Gérard Olivier, Jean-Luc Velay   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A small scale study into the effect that text & background colour has on processing and self-correction rates for childrens’ on-screen reading [PDF]

, 2010
Pedagogical practices in formal educational settings together with the nature of communication technologies in the media and elsewhere mean that children will encounter on-screen typography and screen-based learning opportunities in both formal school ...
Whitehead, David, Vanderschantz, Nicholas, Carss, Wendy Diane, Timpany, Claire   +3 more
core   +1 more source

Retention and exam performance based on print book and e-Book study at universities in Sri Lanka

Conservation Science in Cultural Heritage
The mode of reading plays a vital role in signifying the relationship between reading (getting the information) and remembering, which, in the end, transforms into professional skills formation. We looked at the assessment of the study's success in using
Nallainathan Senthuran, Indang Ariati Ariffin, Ali Khatibi, Jacquline Tham   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The effect of age and font size on reading text on handheld computers [PDF]

, 2005
Though there have been many studies of computer based text reading, only a few have considered the small screens of handheld computers. This paper presents an investigation into the effect of varying font size between 2 and 16 point on reading text on a ...
Goodman, J., Brewster, S.A., Gray, P, Gray, P.D.G., ,, Joy Goodman, Iain Darroch, Phil Gray, Darroch, I., Stephen Brewster, Brewster, S, Darroch, I, Goodman, J   +12 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Foretrekker studentene trykte eller elektroniske ressurser?

Nordic Journal of Information Literacy in Higher Education, 2012
A project at the University of Agder has studied the use of e-readers as a tool for academic study. E-readers (Kindle DX and iPad) were loaded with texts from required reading lists in five courses with 94 participating students.
Birgitte Kleivset
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Adults with reading difficulties demonstrate selective impairments in the fine neural tuning for print

Frontiers in Neuroscience
IntroductionNeural tuning for print, reflected in differential responses of the N170 component of event-related potentials to orthographic forms and other visual stimuli, serves as the neural basis for efficient visual word reading.
Tongjie Zhuang, Yaowen Li, Yufei Tan, Jiuju Wang, Xiuyue Yue, Licheng Xue, Jing Zhao, Jing Zhao   +7 more
doaj   +1 more source