Results 121 to 130 of about 34,037 (308)
Applied SciencesThis paper presents an improved knowledge-based genetic algorithm for relay satellite task scheduling. It aims to address the issue of ensuring high-priority tasks under complex constraints and resource competition.
Yiwei Zhao, Liqian Wang, Jingke Zou
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
On closed queueing networks with mixed preemptive resume priority servers. [PDF]
This paper discusses a typical closed queueing network model in which multiple preemptive resume servers are present with different priority structures at each priority node. An algorithm is developed that is applicable for the three-node two-class model
Leemans, Herlinde, Dedene, Guido
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Beam search algorithms for the early/tardy scheduling problem with release dates [PDF]
In this paper we consider the single machine earliness/tardiness scheduling problem with di?erent release dates and no unforced idle time. We present several heuristic algorithms based on the beam search technique. These algorithms include classical beam
Rui A. F. S. Alves, Jorge M. S. Valente
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Explorando descartes de ativações periódicas para provimento de qualidade de serviço em redes IEEE 802.15.4 [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e SistemasAtualmente, tem se considerado cada vez mais o uso de redes sem fios em sistemas de automação industrial e ...
Semprebom, Tiago
core
Mehran University Research Journal of Engineering and TechnologyWireless Multimedia Sensor Networks (WMSNs) can collect video, audio, and scalar data, making them highly valuable for Internet of Things (IoT) applications.
Tehmina Karamat +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source