Results 171 to 180 of about 385,440 (355)

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Prise en charge de la multimorbidité cœur–cerveau : un guide de pratique clinique. [PDF]

CMAJ
Edwards JD, Li Z, McFarlane P, Rabi DM, Gilbert J, Bajaj HS, MacIntosh BJ, Bittman J, Feldman RD, Dresser G, Terenzi K, Swartz R, Gabor J, Pearson GJ, Selby P, Wharton S, Warburton DER, Pakhalé S, Styra R, Baker B, Tu K, Hawkins M, Stone JA, Vaillancourt T, Poon S, Virani SA, Jain R, Jones PH, Sandhu RK, Ganesh A, Andrade JG, Stern S, Habert J, Rivard L, Roumeliotis P, Udell JA, Campbell T, Bacon SL, Trudeau L, Keshavjee K, Pham T, Cheng G, Lewis KB, Maar M, Stacey D, Oldenburg B, Dhukai AR, Pasricha SV, Sherifali D, Racey M, Hua-Stewart D, Gravel CA, Lewis M, Mehta S, Hill MD, Haider N, Lindsay P, Liu P, Tobe SW.   +58 more
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Diagnostic et prise en charge de la maladie cœliaque. [PDF]

CMAJ
Blom JJ, Gidrewicz D, Turner J, Duerksen DR, Pinto-Sánchez MI.   +4 more
europepmc   +1 more source

Prise en charge non chirurgicale de l’hémorragie majeure. [PDF]

CMAJ, 2023
Callum J, Evans CCD, Barkun A, Karkouti K.   +3 more
europepmc   +1 more source

Prise en compte et prise en charge : quelques recommandations

Etudes sur la mort, 2003
Cosette Odier, Maurice Gardiol
openaire   +2 more sources

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Recommandations de pratiques exemplaires pour la prise en charge de l’amyotrophie bulbospinale liée à l’X. [PDF]

CMAJ
Schellenberg KL, Caspar-Bell G, Ellis C, Johnston W, King A, King M, Korngut L, Kushneriuk B, Lavoie AJ, McGonigle R, Newton J, O'Connell C, Shoesmith C, Suchowersky O, Warman-Chardon J, Wunder S, Pfeffer G.   +16 more
europepmc   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source