Results 91 to 100 of about 216,958 (318)

Design of Low-Glared LED Rear Light of Automotive for EU ECE Regulation by Use of Optimized Micro-Prisms Array

Crystals, 2020
A new LED rear light for automotives is proposed and demonstrated for EU ECE R07 regulation. The full rear light is a combination of a position lamp and a braking lamp, and LED light bars and micro-prisms are involved as their essential components.
Hien-Thanh Le, Lanh-Thanh Le, Hsing-Yuan Liao, Ming-Jui Chen, Hsin-Yi Ma, Hsiao-Yi Lee   +5 more
doaj   +1 more source

Stress-strain characteristic of SFRC using recycled fibres

, 2006
This paper presents work from a comprehensive study on the development of a flexural design framework for concrete reinforced with steel fibres that are recovered from used tyres.
Neocleous, K., Pilakoutas, K., Tlemat, H.   +2 more
core   +1 more source

Prisms to Shift Pain Away: Pathophysiological and Therapeutic Exploration of CRPS with Prism Adaptation

Journal of Neural Transplantation and Plasticity, 2016
Complex Regional Pain Syndrome (CRPS) is an invalidating chronic condition subsequent to peripheral lesions. There is growing consensus for a central contribution to CRPS.
L. Christophe, E. Chabanat, L. Delporte, P. Revol, P. Volckmann, S. Jacquin-Courtois, Y. Rossetti   +6 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Optical System Design Method Based on Rotating Risley Prism

IEEE Photonics Journal
As a type of beam steering element, the Risley prism has found extensive applications in the field of optics. A single Risley prism can deflect incident light beams with a constant deviation angle, while a rotating multi-Risley prism system enables ...
Shuaiwei Mu, Shuanglong Tan, Haolin Qi, Han Pei, Lin Ma, Xin Zhang, Hongbo Wu   +6 more
doaj   +1 more source

Computing the Minkowski sum of prisms [PDF]

Within this paper we compute the Minkowski sum of prisms ("Cephoids") in a finite-dimensional vector space. We provide a representation of a finite sum of prisms in terms of inequalities.convex analysis, Minkowski sum ...
Diethard Pallaschke, Joachim Rosenmüller   +1 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

High-Power Prismatic Devices for Oblique Peripheral Prisms

Optometry and Vision Science, 2016
Purpose Horizontal peripheral prisms for hemianopia provide field expansion above and below the horizontal meridian; however, there is a vertical gap leaving the central area (important for driving) without expansion.
E. Peli, A. Bowers, Karen Keeney, Jae-Hyun Jung   +3 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source