Results 111 to 120 of about 216,958 (318)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Effective prism diopter for strabismus measurement: Conversion from anterior Prentice position to posterior parallel position and from glass prism to acrylic prism

Indian Journal of Ophthalmology
Purpose: In clinical ophthalmology, prisms, commonly made of glass, are labeled based on the prism diopter (PD) value measured in the anterior Prentice position.
Leilei Zou, Hong Liu, Shu Wang, Tian Tian, Cheng Fang, Gang Luo, Rui Liu   +6 more
doaj   +1 more source

Imaging with parallel ray-rotation sheets

, 2008
A ray-rotation sheet consists of miniaturized optical components that function - ray optically - as a homogeneous medium that rotates the local direction of transmitted light rays around the sheet normal by an arbitrary angle [A. C.
Courtial, Johannes, Hamilton, Alasdair C.   +1 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Polarizer mechanism for the space telescope faint object spectrograph [PDF]

, 1983
The polarizer mechanism for the Space Telescope Faint Object Spectrograph is described. This device will allow spectropolarimetric measurements of faint astronomical objects. The mechanism employs a unique arrangement to meet functional requirements in a
Thulson, M. D.
core   +1 more source

Design, characterization, and fabrication of solar-retroreflective cool-wall materials [PDF]

, 2020
Raising urban albedo increases the fraction of incident sunlight returned to outer space, cooling cities and their buildings. We evaluated the angular distribution of solar radiation incident on exterior walls in 17 U S.
Berdahl, P, Chen, S, Goudey, H, Harima, T, Levinson, R, Slack, J   +5 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Multiprism collimator [PDF]

, 1982
A special purpose optical collimator system which generates multiple collimated light beams with precisely related angular separation of the beams, is comprised of a stack of relatively flat plate-like refracted prisms in the form of wedges.
Minott, P. O.
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Azimuth laying system Patent [PDF]

, 1968
Inertial gimbal alignment system for spacecraft ...
Mandel, C. H., Thomason, H. E.
core   +1 more source