Results 181 to 190 of about 216,958 (318)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Adult-Acquired Esotropia: Clinical Characteristics, Risk Factors and Outcomes of a Novel Surgical Approach. [PDF]

J Clin Med
Torres García DJ, Pérez Morenilla B, Álvarez Gómez A, González-Cruces T, Díaz-Mesa V, Cerdán Palacios D, Morales Becerra A.   +6 more
europepmc   +1 more source

Improvement of the wavelength switching behavior of semiconductor tunable lasers through optical feedback from a periodic reference filter based on a novel prism-based implementation of a Fox-Smith resonator [PDF]

, 2005
Baets, Roel, Bockstaele, Ronny, Moeyersoon, Bart, Morthier, Geert   +3 more
core   +1 more source

Regularly configured structures with polygonal prisms for three-dimensional auxetic behaviour

Proceedings of the Royal Society A, 2017
Junhyun Kim, Dongheok Shin, D. Yoo, Kyoungsik Kim   +3 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

MuCoSA: Multi-contextual similarity assessment for histopathology image search. [PDF]

J Pathol Inform
Kim GY, Jeon Y, Jeong H, Lee S, Kim H, Lee B, Jung KH, Ho DJ, Choi YL.   +8 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Hunter-Schreger Bands: Clinical Implications and Future Directions, Scoping Review. [PDF]

Int J Dent
Dioguardi M, Guerra C, Illuzzi G, Sanesi L, Sovereto D, Ballini A, Cazzolla AP, Martella A, Lo Muzio L, Zhurakivska K, Tisci A, Troiano G.   +11 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Structured Ternary Fluids Promote Crystallization and Detection of 5‑Methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile (ROY) Metastable Polymorphs. [PDF]

Cryst Growth Des
Shu Y, Maunder JJ, Fröhlich NL, Rolle-Binne M, Cooper SJ.   +4 more
europepmc   +1 more source