Results 61 to 70 of about 216,958 (318)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
No Useful Field Expansion with Full-field Prisms.
Optometry and Vision Science, 2018 SIGNIFICANCE Full-field prisms that fill the entire spectacle eye wire have been considered as field expansion devices for homonymous hemianopia (HH) and acquired monocular vision (AMV).
Jae-Hyun Jung, E. Peli
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Perluasan Masalah Isoperimetrik pada Bangun Ruang
Jambura Journal of Mathematics, 2023 In this paper, several extensions of the isoperimetric problem in solid figures are explored, focusing on oblique and right prisms with rectangular, right-angled triangular, and regular hexagonal bases. The objective of this research is to find the prism
Andri Setiawan +2 more
doaj +1 more source
A remark on the role of indeterminism and non-locality in the violation of Bell's inequality
, 2013 Some years ago Aerts et al. presented a macroscopic model in which the amount of non-locality and indeterminism could be continuously varied, and used it to show that by increasing non-locality one increases, as expected, the degree of violation of Bell ...
de Bianchi, Massimiliano Sassoli
core +1 more source
Journal of the American Chemical Society, 2016 Meridional (mer) coordination promotes the generation of larger and lower-symmetry prismatic metallosupramolecular structures, in contrast with the facial (fac) coordination common to smaller and higher-symmetry polyhedra.
Marion Kieffer +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Variantes terapéuticas del estrabismo restrictivo Therapeutic variants of restricted strabismus
Revista Cubana de Oftalmología, 2009 INTRODUCCIÓN: El estrabismo restrictivo es la secuela más frecuente de la orbitopatía tiroidea. Ocurre por el desplazamiento de los músculos hacia los senos perinasales.
María Cáceres Toledo +1 more
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