Results 61 to 70 of about 543,621 (317)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Integral Privacy [PDF]

open access: yes, 2016
El treball es va presentar a la International Conference on Cryptology and Network Security (15th : 2016 : Milan, Italy) When considering data provenance some problems arise from the need to safely handle provenance related functionality. If some modifications have to be performed in a data set due to provenance related requirements, e.g.
Torra i Reventós, Vicenç   +1 more
openaire   +4 more sources

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Security and Privacy: Why Privacy Matters [PDF]

open access: yesScience and Engineering Ethics, 2013
A long-overdue discussion of security and privacy is taking place within the US and among its friends and associates in many parts of the globe. In large part, this is due to the revelations of Edward Snowden, the employee of a government contractor, who leaked secret information about the extent of US government data collection on the calling habits ...
openaire   +3 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Secure Data Sharing in Smart Homes: An Efficient Approach Based on Local Differential Privacy and Randomized Responses [PDF]

open access: diamond, 2023
Amr Tarek Elsayed   +3 more
openalex   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Transparent Privacy is Principled Privacy

open access: yesHarvard Data Science Review, 2022
In a technical treatment, this article establishes the necessity of transparent privacy for drawing unbiased statistical inference for a wide range of scientific questions. Transparency is a distinct feature enjoyed by differential privacy: the probabilistic mechanism with which the data are privatized can be made public without sabotaging the privacy ...
openaire   +3 more sources

Home - About - Disclaimer - Privacy