Results 51 to 60 of about 7,584,370 (305)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Litigants in Person in Private Family Law Cases [PDF]

open access: yes, 2014
This study was designed to develop the evidence base on litigants in person in private family law cases, including their behavioural drivers, experiences and support needs, and impact on the court prior to the implementation of legal aid reforms in April
Miles, J   +23 more
core  

Post-quantum cryptography-driven security framework for cloud computing

open access: yesOpen Computer Science, 2022
Data security in the cloud has been a major issue since the inception and adoption of cloud computing. Various frameworks have been proposed, and yet data breach prevails.
Ukwuoma Henry Chima   +3 more
doaj   +1 more source

Subjective Cognitive Concerns and Cognitive Trajectories in Parkinson's Disease: Biomarker Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the relationship of subjective cognitive concerns (SCC) with biomarkers of Alzheimer's disease (AD), neurodegeneration, and Parkinson's disease (PD) and domain‐specific cognitive trajectories among cognitively unimpaired persons with de novo PD. Method Cognitively unimpaired participants with SCC (n = 294) and without SCC (
Francesca V. Lopez   +5 more
wiley   +1 more source

Unsolicited Proposals : The Issues for Private Infrastructure Projects

open access: yes, 2003
Many of the world's most controversial private infrastructure projects originated as unsolicited proposals to governments.
World Bank
core   +1 more source

A Graph-Based Public-Key Cryptosystem Using the NP-Complete Problem of Partitioning Into Perfect Matchings

open access: yesIEEE Access
Cryptography serves as the backbone of modern digital security, protecting sensitive information across electronic communication and transactions. The rapid advancement of quantum computing poses a threat to classical cryptographic systems, necessitating
Jane Shonon Cutinha   +2 more
doaj   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan   +4 more
wiley   +1 more source

Secure and efficient two-party ECDSA signature scheme

open access: yesTongxin xuebao, 2021
To solve the easy disclosure of signature private key and excessive concentration of signature rights, a secure and efficient two-party ECDSA signature scheme was proposed for the blockchain based network trading systems.By pre-computing one-time pad ...
Jing WANG, Libing WU, Min LUO, Debiao HE
doaj   +2 more sources

Fault attacks on authenticated encryption modes for GIFT

open access: yesIET Information Security, 2022
There are several authenticated encryption modes for block cipher GIFT in the NIST lightweight cryptography standardisation process. In this study, the authors research on the fault attacks on this kind of authenticated encryption modes and mainly ...
Shuai Liu, Jie Guan, Bin Hu
doaj   +1 more source

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea   +53 more
wiley   +1 more source

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