Results 131 to 140 of about 38,942 (309)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
BusinessFrom Examination and Prizes Committee
BusinessFrom Examination and Prizes CommitteeBusinessFrom Examination and Prizes ...
University of Khartoum
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
RESEARCH PRIZES: A MECHANISM TO REWARD INNOVATION IN AFRICAN AGRICULTURE
This paper identifies market failures that limit agricultural R&D for Africa and other resource-poor environments, and proposes a mechanism to help circumvent them with cash prizes for the dissemination of successful innovations.
Masters, William J.
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Baccalaureate work {\clqq} Nobel prizes in branch of physics". The main subject of this dissertation is awarding Nobel prizes in branch of physics. The work includes general academic and technical possibilities of recent physics, but also last years ...
FIALA, Jan
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Based on the absence of studies on the symbolic capital of the InformationDocumentation profession, ten priority research areas are presented: the study of the impacts of the prizes, the establishment of a taxonomy of the awards, the analysis of ...
Paula Ochôa, Paulo J. S. Barata
doaj
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
19-252019 Nobel Prizes in Physics, Physiology or Medicine ...
Parida, Ramesh Chandra +2 more
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