Results 171 to 180 of about 111,764 (305)

Reduced Paramagnetic Rim Visibility Signals Lesion Aging and Tissue Degeneration in Progressive Multiple Sclerosis: Impact on Clinical Trials. [PDF]

Neurol Neuroimmunol Neuroinflamm
Sacco S, Zhao H, Cheng S, Akula AV, Luskin E, Zhang J, Manouvakhova O, Cooper TP, Stern W, Block VJ, Virupakshaiah A, Gomez R, Santaniello A, Sati P, Papinutto N, Bove R, Gelfand JM, Goodin DS, Green AJ, Oksenberg J, Waubant E, Wilson MR, Zamvil SS, as the University of California, San Francisco MS-EPIC Team, Cree BAC, Hauser SL, Henry RG.   +27 more
europepmc   +1 more source

Targeting the NR3C1‐ACSL4 Axis Triggers Ferroptosis to Overcome Radioresistance in Prostate Cancer

Cancer Science, EarlyView.
The glucocorticoid receptor NR3C1 drives prostate cancer radioresistance by upregulating ACSL4. High ACSL4 levels create a lipid metabolic vulnerability. The clinical agent DHA synergizes with ACSL4 to induce lipid peroxidation and ferroptosis, effectively overcoming radioresistance.
Jing Yang, Puyuan Chen, Yawen Zheng, Feiyue Shi, Min Wang, Luwei Xu, Xiaowei Wei, Xiumei Wang   +7 more
wiley   +1 more source

Increased Attentive Use Is Linked to More Idiosyncratic Functional Connections. [PDF]

J Neurosci
Demirayak P, Fleming LL, Stewart P, Chua R, Visscher KM.   +4 more
europepmc   +1 more source

m6A‐Mediated Stabilization of MRPS23 Drives NSCLC Progression Via HSPA8 and ERK Signaling Modulation

Cancer Science, EarlyView.
MRPS23 mRNA is m6A‐methylated by WTAP and stabilized by IGF2BP3, leading to increased MRPS23 protein. MRPS23 physically interacts with HSPA8, and this interaction is functionally associated with activation of the RAS–RAF–MEK–ERK pathway, ultimately promoting NSCLC cell proliferation and tumor progression.
Sihong Le, Yitao Le, Xianshen Sha, Feng Qiu, Ling Zhang   +4 more
wiley   +1 more source

Molecular Characterization, Signaling Activity, and Expression Profiles of a Novel Prolactin Splice Variant (PRL-S) in Zhedong White Geese Across Reproductive States. [PDF]

Int J Mol Sci
Zhao X, Wang S, Wang C, Zhao P, Pan Y, Zeng C, Zhang Y, Yue S, Huang H, Wang Q.   +9 more
europepmc   +1 more source

Prevalence and Sociodemographic Variation of Allergic Diseases in Australia: Findings From the Australian National Health Survey

Clinical &Experimental Allergy, EarlyView.
Using data from 17,093 participants in the 2022 Australian National Health Survey, this study is the first to report nationwide prevalence estimates for allergic rhinitis (23.9%), food allergy (7.0%), drug allergy (5.2%), eczema (1.6%) and diagnosed asthma (10.8%) across Australia.
Yichao Wang, Jennifer J. Koplin, Janet M. Davies, Constance H. Katelaris, Debra J. Palmer, Jason A. Trubiano, Joy Lee, Michaela Lucas, Michael O′Sullivan, Sandra Vale, Sheryl van Nunen, Troy Wanandy, Dianne E. Campbell, Kirsten P. Perrett, Rachel L. Peters   +14 more
wiley   +1 more source

The National Allergy Centre of Excellence–Addressing Australia's Allergy Burden

Clinical &Experimental Allergy, EarlyView.
Australia's high allergy burden prompted a national response, leading to the establishment of the National Allergy Centre of Excellence (NACE) in 2022. The NACE has advanced research infrastructure, collaboration, and consumer‐centred care through four pillars, achieving global recognition and accelerating translation into policy, practice, and ...
A. Young, J. J. Koplin, D. E. Campbell, J. M. Davies, H. Edmund, T. Jamieson, C. J. Hornung, T. O'Farrell, D. West, E. Kayes, L. A. Gray, R. L. Peters, L. Gamble, K. Gwynne, J. Lee, M. Lucas, C. H. Katelaris, M. D. O'Sullivan, D. J. Palmer, J. Trubiano, S. van Nunen, S. L. Vale, T. Wanandy, K. P. Perrett   +23 more
wiley   +1 more source

Differences in Preferred Retinal Loci of Fixation in Binocular and Monocular Vision. [PDF]

Invest Ophthalmol Vis Sci
Freiberg M, Gutnikov A, Meltendorf C, Reiss S, Krüger R, Harmening W.   +5 more
europepmc   +1 more source

ch PRL –siRNA IGF1 anterior pituitary

, 2014
Not AvailableUp-regulation of the chicken prolactin (chPRL) has been implicated in incubation behavior in galliforms that induces broodiness and gonadal involution.
Mondal S, Mishra A, Reddy IJ
core  

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source