Results 211 to 220 of about 111,764 (305)

An endocrine microbe immunity framework for granulomatous mastitis toward phenotype-oriented interpretation. [PDF]

iScience
Jiang Y, Yang K, Xue B, Wang Y, Jia H.
europepmc   +1 more source

Essential, Yet Precarious, Mistreated, Sick and Medicalized: A Sequential Explanatory Mixed‐Methods Study on Homecare Aides in Spain

American Journal of Industrial Medicine, Volume 69, Issue 10, Page 814-829, October 2026.
ABSTRACT Background Homecare aides (HCAs) are professional non‐family caregivers, who support dependent individuals to live at home with dignity; yet in Spain they remain understudied and vulnerable, often facing precarious working conditions. We aimed to characterize HCAs’ employment, living conditions, health, and exposure to workplace violence and ...
Albert Navarro‐Giné, Pedro Ferrer‐Rosende, Maria Feijoo‐Cid, Sergio Salas‐Nicás, Laura Esteve‐Matalí, Valeria Stuardo‐Ávila, María Isabel Fernández‐Cano   +6 more
wiley   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2149-2159, October 2026.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

β2 Adrenoceptor Signaling Modulates Myoblast Differentiation via miR‐374b‐5p/GSK3β and miR‐326‐3p/Tnfrsf11a Axes

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Myoblast differentiation is a crucial step of skeletal muscle regeneration and is impaired in the absence of the β2 adrenoceptor (ADRβ2). Since miR‐374b and miR‐326 regulate cell differentiation, this study investigated if ADRβ2 regulates myoblast differentiation via miR‐374b‐5p and miR‐326‐3p. Primary myoblasts from ADRβ2 knockout (β2KO) mice
Tatiana E. Koike, Cesar S. Fuziwara, Audrei R. Santos, Fernanda V. B. Delpupo, Tábata L. Nascimento, Andrei Rozanski, Marcelo G. Pereira, Patrícia C. Brum, Edna T. Kimura, Thomas A. Rando, Elen H. Miyabara   +10 more
wiley   +1 more source

Prolactin as a Candidate Biomarker in Non-Small Cell Lung Cancer: Implications for Personalized Medicine and Post-Treatment Risk Stratification. [PDF]

J Pers Med
Gajewski F, Kurec G, Litkowska A, Pec J, Kleinrok J, Pająk W, Burdan O, Krawczyk P, Korolczuk A.   +8 more
europepmc   +1 more source

Chronic Central Adrenal Insufficiency in a Patient With Remote Traumatic Brain Injury and an Apparently Adequate Standard‐Dose ACTH Response: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In patients with a remote history of traumatic brain injury, central adrenal insufficiency may remain unrecognized for decades. An apparently adequate response to standard‐dose ACTH stimulation should not preclude further evaluation of the hypothalamic–pituitary–adrenal axis when clinical and biochemical findings continue to suggest adrenal ...
Kazunori Kageyama, Keisuke Sato, Satoshi Yamagata, Mizuki Tasso, Yuki Nakada, Shojiro Sawada   +5 more
wiley   +1 more source

USP25 stabilises GLI1 through K48‐linked deubiquitination within a reciprocal regulatory circuit in osteoarthritis models

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
GLI1‐centred USP25‐GLI1 reciprocal regulation in OA‐relevant models. Hedgehog/GLI1 signalling transcriptionally reinforces USP25 expression, while USP25 deubiquitinates and stabilises GLI1. This reciprocal circuit is associated with inflammatory and cartilage‐catabolic changes in the tested models.
Qian Zhang, Yinyan Ye, Yijie Huang, Jun Li, Dongfeng Huang   +4 more
wiley   +1 more source

Phosphatases of regenerating liver downregulate PTEN to promote tumorigenesis. [PDF]

Biochem Soc Trans
Abou-Shanab AM, Yu J, Bai Y, Zhang ZY.
europepmc   +1 more source

The Effect of N‐Acetyl Cysteine on Serum Lipid Profile and Heavy Metals in Women With Endometriosis Undergoing ICSI: A Randomized Controlled Trial

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims Endometriosis is associated with oxidative stress and heavy metal accumulation. This study evaluated whether N‐acetylcysteine (NAC) reduces serum heavy metals and improves lipid profiles in women with endometriosis undergoing fertility treatment.
Fatemeh Khorasani, Parvaneh Mirabi, Sedighe Esmaeilzadeh   +2 more
wiley   +1 more source

Deep Learning-Based Automated Detection and Burden Assessment of Paramagnetic Rim Lesions on Quantitative Susceptibility Mapping in Patients With Multiple Sclerosis. [PDF]

Korean J Radiol
Jeong E, Seo D, Moon HH, Yun H, Choi Y, Lee EJ.   +5 more
europepmc   +1 more source