Results 221 to 230 of about 111,764 (305)

The Role of Dendritic Spines in Water Exchange Measurements With Diffusion MRI: Time‐Dependent Single Diffusion Encoding MRI

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Geometric exchange between dendritic spines and shafts is often neglected, yet it exhibits the same signature as permeative exchange, biasing NEXI/SMEX measurements. We propose two models: an extended three‐compartment Kärger model that resolves spine–shaft exchange explicitly, and a coarse‐grained Kärger model that absorbs spines into an effective ...
Kadir Şimşek, Arthur Chakwizira, Markus Nilsson, Marco Palombo   +3 more
wiley   +1 more source

The influence of hormonal changes during pregnancy on bone metabolism - a mini review. [PDF]

Front Endocrinol (Lausanne)
Brona A, Stachowska B, Bolanowski M, Halupczok-Żyła J.   +3 more
europepmc   +1 more source

Immune dysregulation in the prostates of C57BL/6Aire−/− mice mirrors that seen in human benign prostatic hyperplasia

The Journal of Pathology, Volume 270, Issue 2, Page 211-225, October 2026.
Abstract Benign prostatic hyperplasia (BPH) is the most common urologic disease in aging men, resulting in significant morbidity. The etiologies of BPH are unknown, though chronic prostatic inflammation is known to promote hyperplasia, fibrotic remodeling, and therapeutic resistance in BPH.
Nadia A Lanman, Meaghan M Broman, Harish Kothandaraman, Gregory M Cresswell, Gada D Awdalkreem, Dilinaer Wusiman, Andree K Kolliegbo, Alexander P Glaser, Brian T Helfand, Renee E Vickman, Jiang Yang, Simon W Hayward, Timothy L Ratliff   +12 more
wiley   +1 more source

Prolactin receptor overexpression in pregnancy-associated Cushing syndrome and functional implications. [PDF]

JCEM Case Rep
Naka M, Ishiwata K, Suzuki S, Kouchi Y, Kishimoto T, Yokote K.   +5 more
europepmc   +1 more source

Securidaca inappendiculata Extract Mitigates Joint Damage in Collagen‐Induced Arthritis Rats Through Modulation of the SIRT1/HIF‐1α/Glycolysis Pathway

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Securidaca inappendiculata (SI) Hassk. is a traditional Chinese herbal medicine commonly used in Southern China for the treatment of rheumatoid arthritis (RA). However, its exact mechanism of action remains unclear. In this study, we evaluated the therapeutic effects of the SI‐derived compound 1,7‐dihydroxy‐3,4‐dimethoxyxanthone (XAN) in a ...
Yuyan Zhou, Yuyun Zhou, Ruoxuan Xiang, Xin Liu, Ting Wang, Xuan Chen, Guodong Wang   +6 more
wiley   +1 more source

Lower prolactin levels are associated with histological severity of metabolic dysfunction-associated steatotic liver disease. [PDF]

BMC Endocr Disord
Ma H, Zhang P, Fang D, Bi Y, Gu T.
europepmc   +1 more source

Hepatocyte Growth Hormone Receptor Ablation Is Associated With Aging Phenotypes and Hepatic Mitochondrial Dysfunction

Aging Cell, Volume 25, Issue 10, October 2026.
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang, Yuli Jian, Fusheng Pang, Ming Ying, Qian Yang, Nian Liu, Shujing Wang, Yingjie Wu   +7 more
wiley   +1 more source

Correlation of type 3 secretion system genes with antimicrobial resistance in <i>Pseudomonas aeruginosa</i>: A unique clinical signature. [PDF]

J Taibah Univ Med Sci
Afaque F, Hayat A, Gul S, Ahmed A, Kazmi M.   +4 more
europepmc   +1 more source

Serotonin engages divergent 5‐HT receptor pathways for cell type‐resolved modulation of prefrontal layer 5 microcircuits

British Journal of Pharmacology, Volume 183, Issue 19, Page 5832-5853, October 2026.
Serotonin differentially modulates layer 5 mPFC microcircuits through cell type‐specific pre‐ and postsynaptic receptor pathways. Presynaptic 5‐HT1BRs suppress glutamate and GABA release, whereas presynaptic and postsynaptic 5‐HT3ARs enhance fast‐spiking interneuron activity, whilst distinct pyramidal neuron subtypes exhibit divergent 5‐HT1AR‐ and 5 ...
Ramya Rama, Guanxiao Qi, Gabriele Radnikow, Danqing Yang, Dirk Feldmeyer   +4 more
wiley   +1 more source

Predictors of in vitro response to somatostatin and dopamine receptor‐targeted treatments are lacking in clinically non‐functioning pituitary tumors

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Clinically non‐functioning pituitary neuroendocrine tumors (NF‐PitNETs) lack effective medical therapies, and the role of somatostatin receptor ligands (SRLs) and dopamine agonists (DAs) in this setting is controversial. We evaluated the in vitro response of NF‐PitNETs to multiple SRL and/or DA treatments, focusing on the role of receptor ...
Claudia Campana, Jessica Amarù, Diego Criminelli Rossi, Anna Arecco, Paolo Nozza, Mara Boschetti, Gianluigi Zona, Diego Ferone, Marica Arvigo, Federico Gatto   +9 more
wiley   +1 more source