Results 51 to 60 of about 170,345 (285)

Properties of Subjects in Bantu Languages [PDF]

open access: yes, 2010
A handout of a presentation given at the Afranaph Project Development Workshop on December 11, 2010, at Rutgers University in New Jersey.This handout discusses how subject words function in various Bantu languages.
Carstens, Vicki   +5 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Case morphology and radical pro-drop

open access: yes, 2008
This paper focuses on the so-called discourse pro-drop languages, i.e., those permitting radical pro-drop, which affects not just subjects, but other pronominal arguments too. Whereas previous attempts to understand the properties of these languages have focused on verbal ...
Neeleman, A, Szendroi, K
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Null Subjects in Non-Pro-Drop Languages: The Lens on French

open access: yesLanguages
The contrast between languages such as Italian that allow subjects of tensed sentences to be null (i.e., pro-drop languages) and those like French that do not (i.e., non-pro-drop languages) is a classic issue for comparative syntactic research ...
Mara Frascarelli, Giorgio Carella
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

NULL SUBJECTS IN OLD GERMANIC LANGUAGES

open access: yesФілологічні студії, 2020
The article outlines the approaches to defining universal subjecthood properties from cognitive, generative, and functional perspectives. Three types of languages are distinguished according to the type of null subjects they allow – pro-drop, topic-drop,
Г. Зінченко
doaj   +1 more source

Taraldsen’s generalization in diachrony : evidence from a diachronic corpus [PDF]

open access: yes, 2016
International audienceWe present the first large scale quantitative investigation of the syncretisation of verbal subject agreement in Medieval French and test a classic analysis which relates non-syncretic agreement and null subjects as parts of the ...
Crabbé, Benoît   +2 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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