Results 131 to 140 of about 961,325 (300)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
This study investigates the relationship between materialism and pro-environmental behavior, focusing on the moderating role of narcissism in the attitude–behavior gap.
Linas Pupelis, Beata Šeinauskienė
doaj +1 more source
Competitive Altruism and Endogenous Reference Group Selection in Private Provision of Environmental Public Goods [PDF]
We develop and test a model of social comparison in which individuals gain status through pro-social behavior (competitive altruism) and in which they endogenously choose the reference group and associated reference standard involved in signaling status (
Kühling, Jan, Welsch, Heinz
core
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Pro-environmental behavior : On the interplay of intrinsic motivations and external conditions [PDF]
A key issue for ecological economics concerns the processes whereby people engage in ecologically responsible behavior and contribute to environmental quality even when they involve a personal cost for a shared benefit.
Padilla, Emilio, Silvi, María Teresa
core
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Purpose-The research examines the environmental literacy of the VIII grade students of SMP Negeri 1 Banawa based on four principal indicators: ecological knowledge, cognitive skills, environmental affect, and pro-environmental behavior. The research aims
Nurasyah Dewi Napitupulu +5 more
doaj +1 more source
More “Nudging” for pro-environmental behavior
The effects of global warming became aware for every one during the last years. Most of the scientists support the opinion that the partly rough changes in the climate and the pollution of the planet are closely related to the behavior of the peoples around the world.
openaire +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Energy Policy Options - from the Perspective of Public Attitudes and Risk Perceptions [PDF]
In the present study a representative sample (N = 797) of the Swedish population was surveyed, with regard to attitudes related to energy policy issues (e.g., environmental attitudes, risk perceptions, and attitudes towards different energy production ...
Viklund, Mattias
core

