Results 141 to 150 of about 958,828 (301)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Energy Policy Options - from the Perspective of Public Attitudes and Risk Perceptions [PDF]

open access: yes
In the present study a representative sample (N = 797) of the Swedish population was surveyed, with regard to attitudes related to energy policy issues (e.g., environmental attitudes, risk perceptions, and attitudes towards different energy production ...
Viklund, Mattias
core  

How the Supreme Court Uses the Certiorari Process in the Ninth Circuit To Further Its Pro-Business Agenda: A Strange Pas de Deux with an Unfortunate Coda [PDF]

open access: yes, 2014
This Article examines the proposition that the Roberts Court has an unusually strong pro-business slant through the lens of the Court\u27s certiorari process.
Babcock, Hope M.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Why it is so hard to predict our partner's product preferences : the effect of target familiarity on prediction accuracy. [PDF]

open access: yes
Many buying decisions require predictions of another person's product attitudes. Yet, consumers are often inaccurate predictors, even for familiar others.
Lerouge, D, Warlop, Luk
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Survival of the Conformist: Social Pressure and Renewable Resource Management [PDF]

open access: yes
This paper examines the role of pro-social behavior as a mechanism for the establishment and maintenance of cooperation in resource use under variable social and environmental conditions.
Alessandro Tavoni   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Creating Low-carbon Communities: Evaluating the Role of Individual Agency and Systemic Inequality in San Jose, CA [PDF]

open access: yes, 2019
Following a scholarly need to test compelling community level sociodemographic representations of environmental behaviors and outcomes, a sequential mixed method approach was used to evaluate the connections of human agency and systemic inequalities with
Ronald, Erin Jessica
core   +2 more sources

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