We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Teaching pro-environmental rules: Implications for environmental education and climate change
The concern regarding the gap between words and actions has spread through different contexts, in particular those relating to environmental education.
Leidy-Vanessa Díaz-Beltrán +1 more
doaj +1 more source
Will Costliness Amplify the Signalling Strength of Past Pro-Environmental Behaviour? Exploratory Study on Autonomy. [PDF]
Bai S, Wang Y, She S, Wei S.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The Impact of an Authoritarian Personality on Pro-Environmental Behaviour for Air Pollution Mitigation through Interactions with Social Norms. [PDF]
Cao J, Chen J.
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
How I See Me-A Meta-Analysis Investigating the Association Between Identities and Pro-environmental Behaviour. [PDF]
Udall AM +3 more
europepmc +1 more source
Revisiting influence of marketing effectiveness and environmental awareness on buying behaviour of green product: a SEM approach [PDF]
Environmental sustainability become a prominent and unending issue in the third world economic countries such as Malaysia. Although, “green” and “go green” concepts were emphasized by academicians and practitioners to explain the need to save the earth
Ahmad, Fais +3 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Impact of Environmental Moral Education on Pro-Environmental Behaviour: Do Psychological Empowerment and Islamic Religiosity Matter? [PDF]
Begum A +5 more
europepmc +1 more source

