Results 141 to 150 of about 3,051,760 (306)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

The effect of a cognitive behavioral exercise program on the pro-inflammatory and anti-inflammatory cytokines [PDF]

, 2012
Objective: The purpose of this study is to investigate the effects of Mindfulness-Based Exercise Program (MBEP) on pro-inflammatory cytokines (Interferon –γ and Tumor Necrosis Factor - α) and anti-inflammatory cytokines (Interleukin – 4 and Interleukin -
Panke, Rutika
core  

Cytotoxicity and Immunomodulatory Effects of Cannabidiol on Canine PBMCs: A Study in LPS-Stimulated and Epileptic Dogs

Animals
Cannabidiol, the primary non-psychoactive phytocannabinoid found in cannabis, has generated significant research interest due to its potential for biological effects, such as anti-inflammatory, analgesic, immunomodulatory, and anticonvulsant properties ...
Phannicha Kosukwatthana, Oumaporn Rungsuriyawiboon, Jatuporn Rattanasrisomporn, Kanogwan Kimram, Natthasit Tansakul   +4 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Canine Pro-inflammatory Cytokines [PDF]

, 2022
openaire   +1 more source

Cytokine status in patients with chronic obstructive pulmonary disease and its relationships with bone tissue function

Терапевтический архив, 2004
Aim. To study cytokine status in patients with chronic obstructive pulmonary disease (COPD) and its interrelations with bone metabolism. Material and methods.
E A Kochetkova, M V Volkova, T N Surovenko, B I Geltser   +3 more
doaj  

Major Depressive Disorder in Long COVID and Exposure to Pro‐Inflammatory Cytokines During Infection by SARS‐CoV‐2

Psychiatric Research and Clinical Practice
Objective Major Depressive Disorder (MDD) is common in long COVID syndrome; however, the neurobiological mechanisms are unclear. An immune activation response has been associated with COVID‐19 severity as well as in MDD.
Hernan F. Guillen‐Burgos, Juan F. Gálvez‐Flórez, Sergio Moreno‐López, Sabrina Wong, Angela T. H. Kwan, Mariana Ramirez‐Posada, Juan‐Manuel Anaya, Roger S. McIntyre   +7 more
doaj   +1 more source

The Mechanism of GABA in Attenuating Neuroinflammation in Alzheimer’s Disease: CP/CEBPα/miR-34a-Mediated Suppression of HDAC2/3 in Astrocytes

Foods
As a widely available dietary supplement, γ-Aminobutyric acid (GABA) exhibits potential for early intervention against Alzheimer’s disease (AD). This study demonstrates that GABA alleviates AD neuroinflammation, and its suppression of astrocytic pro ...
Jingzhu Zhang, Sining Wu, Na Meng, Cui Li, Yue Zhao, Li An   +5 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Association of self-reported symptoms with serum levels of vitamin D and multivariate cytokine profile in healthy women

Journal of Inflammation Research, 2017
Fawaz Y Azizieh,1 Khulood O Alyahya,2 Kamaludin Dingle1 1Department of Mathematics and Natural Sciences, Gulf University for Science and Technology, International Centre for Applied Mathematics and Computational Bioengineering, West Mishref, Kuwait ...
Azizieh FY, Alyahya KO, Dingle K
doaj