Results 201 to 210 of about 493,090 (289)

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

open access: yesAdvanced Science, EarlyView.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen   +14 more
wiley   +1 more source

BROAD‐NESS Uncovers Dual‐Stream Mechanisms Underlying Predictive Coding in Auditory Memory Networks

open access: yesAdvanced Science, EarlyView.
BROADband Network Estimation via Source Space (BROAD‐NESS) is a flexible analytical pipeline for identifying large‐scale brain networks from event‐related, source‐reconstructed MEG data, with a focus on auditory predictive and memory processes. BROAD‐NESS integrates a suite of complementary tools, including PCA‐based decomposition, phase space, and ...
Leonardo Bonetti   +8 more
wiley   +1 more source

Genomic privacy and security in the era of artificial intelligence and quantum computing. [PDF]

open access: yesDiscov Comput
Annan R   +5 more
europepmc   +1 more source

Butterfly‐Shaped Guest Molecules Enable Tunable Room‐Temperature Phosphorescence in Host‐Guest Doped Systems

open access: yesAdvanced Science, EarlyView.
Butterfly‐shaped triphenylamine‐based guest molecules (DBDBD) doped into rigid host matrices (TPP, CA) achieve efficient, multicolor‐tunable room‐temperature phosphorescence (RTP). The host‐guest synergy enables ultralong afterglow (up to 4 s) and quantum yields (Φp = 3.42%), with applications in dynamic anti‐counterfeiting and information encryption ...
Zongyong Lou   +5 more
wiley   +1 more source

Allele‐Specific Regulation of PAXIP1‐AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice

open access: yesAdvanced Science, EarlyView.
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni   +14 more
wiley   +1 more source

Privacy-preserving framework for genomic computations via multi-key homomorphic encryption. [PDF]

open access: yesBioinformatics
Namazi M   +3 more
europepmc   +1 more source

STEMDiff: A Wavelet‐Enhanced Diffusion Model for Physics‐Informed STEM Image Generation

open access: yesAdvanced Science, EarlyView.
STEMDiff, which is a conditional diffusion model that generates realistic STEM images from crystal structure‐derived binary labels, is proposed, overcoming high‐frequency bias via a Discrete Wavelet Transform‐based architecture. It produces experimentally indistinguishable images, enabling annotation‐free training of networks for precise atomic ...
Yihui Bao   +4 more
wiley   +1 more source

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