Results 61 to 70 of about 505,863 (290)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Signcryption schemes with insider security in an ideal permutation model

open access: yesJournal of Mathematical Cryptology, 2019
Signcryption aims to provide both confidentiality and authentication of messages more efficiently than performing encryption and signing independently. The “Commit-then-Sign & Encrypt” (CtS&E) method allows to perform encryption and signing in parallel ...
Bansal Tarun Kumar   +2 more
doaj   +1 more source

CCA1 secure FHE from PIO, revisited

open access: yesCybersecurity, 2018
Fully data using only public information. So far, most FHE schemes are CPA secure. In PKC 2017, Canetti et al. extended the generic transformation of Boneh, Canetti, Halevi and Katz to turn any multi-key identity-based FHE scheme into a CCA1-secure FHE ...
Biao Wang, Xueqing Wang, Rui Xue
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Public Key Protocols from Twisted-Skew Group Rings

open access: yesCryptography
This article studies some algebraic structures known as twisted-skew group rings in the context of public key cryptography. We first present some background related to these structures to then specifically introduce particular twisted-skew group rings ...
Javier de la Cruz   +3 more
doaj   +1 more source

Onboard disease prediction and rehabilitation monitoring on secure edge-cloud integrated privacy preserving healthcare system

open access: yesEgyptian Informatics Journal, 2021
Edge-based privacy preserving cryptosystem is identified as the upcoming amenities of cloud-based secure remote healthcare monitoring systems. Usually, the cloud-based healthcare system will directly collect the remote patient data through a sensor layer
Ramaprabha Jayaram, S. Prabakaran
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

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