Results 191 to 200 of about 20,022 (282)

Defining physician-AI collaboration in pulmonary and critical care medicine: concepts and illustrative examples for clinical reasoning. [PDF]

ATS Sch
Vaezi A, Ashby T, Kadir S, Schweitzer M, Hadeh A, Sen P, Seeram V, Mirsaeidi M.   +7 more
europepmc   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

Enhancing context-aware SARS disorder management: a proposed multi-agent simulation framework with machine learning and bio-sensor data integration. [PDF]

Front Med Technol
Abdullah, Fatima Z, Hafeez N, Ather MA, Tellez RQ, Sidorov G, Sánchez-Mejorada CG, Torres Ruiz MJ.   +7 more
europepmc   +1 more source

Bayesian inference in probabilistic graphical models.

, 2017
This thesis consists of four papers studying structure learning and Bayesian inference in probabilistic graphical models for both undirected and directed acyclic graphs (DAGs). Paper A presents a novel algorithm, called the Christmas tree algorithm (CTA), that incrementally construct junction trees for decomposable graphs by adding one node at a time ...
openaire   +2 more sources

Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC

Advanced Science, EarlyView.
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang, Lin Ding, Yu Zhong, Haokang Feng, Linglong Huang, Waidong Huang, Chunqing Wang, Arne Östman, Beili Wang, Jian Zhou, Jia Fan, Wei Guo, Liang Wu, Yunfan Sun   +13 more
wiley   +1 more source

Multimodal bioinformatic analyses of genome-scale expression beyond gene-centric differential expression. [PDF]

Brief Bioinform
Nuanpirom J, Charoensawan V.
europepmc   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

Epistemic uncertain computing for intrusion detection with explainability & multi-criteria optimization using AA-NLS and GRUSO-GRU. [PDF]

Sci Rep
Kiruthika K, Karpagam M, Sardar TH, Hassan SM.   +3 more
europepmc   +1 more source

Self‐Adaptive Non‐Flammable Wallpaper With Layered Bead‐Network Structure for Light Path Modulation Enabling on‐Demand Building Thermal Management

Advanced Science, EarlyView.
A layered bead‐network wallpaper is designed to modulate the light propagation path, overcoming the color residue limitations of thermochromic components for efficient automatic switching between radiative cooling and solar heating modes. The layered bead‐network wallpaper provides passive, all‐season thermal regulation while offering self‐cleaning and
Jianyu Wu, Linmin Xia, Jiankun Wu, Yuying Yang, Wuhong Zhong, Jianguo Li, Yan Yu, Rilong Yang   +7 more
wiley   +1 more source

A guide to bayesian networks software for structure and parameter learning, with a focus on causal discovery tools. [PDF]

Front Syst Biol
Canonaco F, Gaudillo J, Astrologo N, Stella F, Acerbi E.   +4 more
europepmc   +1 more source