Results 61 to 70 of about 514,307 (282)

Evaluating probabilistic programming and fast variational Bayesian inference in phylogenetics [PDF]

open access: yesPeerJ, 2019
Recent advances in statistical machine learning techniques have led to the creation of probabilistic programming frameworks. These frameworks enable probabilistic models to be rapidly prototyped and fit to data using scalable approximation methods such ...
Mathieu Fourment, Aaron E. Darling
doaj   +2 more sources

Diffeological Statistical Models, the Fisher Metric and Probabilistic Mappings [PDF]

open access: yesMathematics, 2020
We introduce the notion of a C k -diffeological statistical model, which allows us to apply the theory of diffeological spaces to (possibly singular) statistical models. In particular, we introduce a class of almost 2-integrable C k -diffeological statistical models that encompasses all known statistical models for which the Fisher metric
openaire   +4 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Likelihood Inference for Models with Unobservables: Another View

open access: yes, 2010
There have been controversies among statisticians on (i) what to model and (ii) how to make inferences from models with unobservables. One such controversy concerns the difference between estimation methods for the marginal means not necessarily having a
Lee, Youngjo, Nelder, John A.
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Network Plasticity as Bayesian Inference

open access: yes, 2015
General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing.
Habenschuss, Stefan   +3 more
core   +3 more sources

Probabilistic Design of Wind Turbines

open access: yesEnergies, 2010
Probabilistic design of wind turbines requires definition of the structural elements to be included in the probabilistic basis: e.g., blades, tower, foundation; identification of important failure modes; careful stochastic modeling of the uncertain ...
Henrik S. Toft, John D. Sørensen
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A statistical model for forecasting probabilistic epidemic bands for dengue cases in Brazil

open access: yesInfectious Disease Modelling
Dengue is a vector-borne disease and a major public health concern in Brazil. Its continuing and rising burden has led the Brazilian Ministry of Health to request for modelling efforts to aid in the preparedness and response to the disease.
Laís Picinini Freitas   +15 more
doaj   +1 more source

PROBABILISTIC-STATISTICAL MODEL OF CHILDREN’S HEALTH

open access: yesВопросы современной педиатрии, 2009
The article continues the series of publications on development of informational system of interdisciplinary monitoring of children’s and adolescents’ health. The results of factor analysis, obtained during examination of more than 10,000 schoolchildren of 1–11 forms living in Moscow, Vologda, Nalchik, Reutov, Petropavlovsk-Kamchatskiy cities are ...
S.M. Chechel’nitskaya   +5 more
openaire   +2 more sources

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