Results 91 to 100 of about 2,751,841 (314)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Crossing probabilities for Voronoi percolation [PDF]

open access: yes, 2014
We prove that the standard Russo-Seymour-Welsh theory is valid for Voronoi percolation. This implies that at criticality the crossing probabilities for rectangles are bounded by constants depending only on their aspect ratio.
V. Tassion
semanticscholar   +1 more source

Une nouvelle méthode pour estimer l’âge au décès des adultes à partir de la surface sacro-pelvienne iliaque

open access: yesBulletins et Mémoires de la Société d’Anthropologie de Paris, 2005
Many studies have shown that the method proposed by Lovejoy et al. (1985) to assess adult age at death from the sacro-pelvic surface of the ilium is not reliable.
Aurore Schmitt
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Chances and risks in medical risk communication

open access: yesGMS German Medical Science, 2015
Communication between physicians and patients in everyday life is marked by a number of disruptive factors. Apart from specific interests, mistakes, and misunderstandings on both sides, there are main factors that contribute to the risk in risk ...
Hoffrage, Ulrich, Koller, Michael
doaj   +1 more source

Probabilities in Session Types [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2019
This paper deals with the probabilistic behaviours of distributed systems described by a process calculus considering both probabilistic internal choices and nondeterministic external choices.
Bogdan Aman, Gabriel Ciobanu
doaj   +1 more source

What probability probably isn't [PDF]

open access: yesAnalysis, 2014
Joyce and others have claimed that degrees of belief are estimates of truth-values and that the probability axioms are conditions of admissibility for these estimates with respect to a scoring rule penalising inaccuracy. In this paper I argue that the claim that the rules of probability are truth-directed in this way depends on an assumption which is ...
openaire   +2 more sources

Probabilities in the inflationary multiverse

open access: yes, 2005
Inflationary cosmology leads to the picture of a "multiverse," involving an infinite number of (spatially infinite) post-inflationary thermalized regions, called pocket universes.
Alexander Vilenkin   +11 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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