Results 81 to 90 of about 3,369,331 (380)

GENESIS – The GENEric SImulation System for Modelling State Transitions

open access: yesJournal of Open Research Software, 2017
This software implements a discrete time Markov chain model, used to model transitions between states when the transition probabilities are known 'a priori'.
Matthew S. Gillman
doaj   +1 more source

Safe probability [PDF]

open access: yesJournal of Statistical Planning and Inference, 2018
Submitted to a ...
openaire   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Good Fences Make for Good Neighbors but Bad Science: A Review of What Improves Bayesian Reasoning and Why

open access: yesFrontiers in Psychology, 2015
Bayesian reasoning, defined here as the updating of a posterior probability following new information, has historically been problematic for humans. Classic psychology experiments have tested human Bayesian reasoning through the use of word problems and ...
Gary L. Brase, W. Trey eHill
doaj   +1 more source

Probability logic. [PDF]

open access: yesNotre Dame Journal of Formal Logic, 1984
The paper opens with a brief historical sketch of the many varied conceptions of the subject which have been considered. Confined to the propositional level, a logic is then presented in which the notion of probability replaces that of truth. Superficially a many-valued logic, it differs from what has heretofore been studied as many-valued logic in ...
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

An Eye-Tracking Study of Statistical Reasoning With Tree Diagrams and 2 × 2 Tables

open access: yesFrontiers in Psychology, 2019
Changing the information format from probabilities into frequencies as well as employing appropriate visualizations such as tree diagrams or 2 × 2 tables are important tools that can facilitate people’s statistical reasoning.
Georg Bruckmaier   +3 more
doaj   +1 more source

Empirical interpretation of imprecise probabilities [PDF]

open access: yes, 2017
This paper investigates the possibility of a frequentist interpretation of imprecise probabilities, by generalizing the approach of Bernoulli’s Ars Conjectandi.
Cattaneo, Marco
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Market-Implied Risk-Neutral Probabilities, Actual Probabilities, Credit Risk and News

open access: yesIIMB Management Review, 2011
Motivated by the credit crisis, this paper investigates links between risk-neutral probabilities of default implied by markets (e.g. from yield spreads) and their actual counterparts (e.g. from ratings).
Shashidhar Murthy
doaj   +3 more sources

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