Results 61 to 70 of about 638,423 (309)

Personal probabilities of probabilities [PDF]

open access: yesTheory and Decision, 1975
By definition, the subjective probability distribution of a random event is revealed by the (‘rational’) subject's choice between bets — a view expressed by F. Ramsey, B. De Finetti, L. J. Savage and traceable to E. Borel and, it can be argued, to T. Bayes.
Jacob Marschak   +13 more
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Liquefaction of Tangier soils by using physically based reliability analysis modelling

open access: yesMATEC Web of Conferences, 2012
Approaches that are widely used to characterize propensity of soils to liquefaction are mainly of empirical type. The potential of liquefaction is assessed by using correlation formulas that are based on field tests such as the standard and the cone ...
Dubujet P.   +3 more
doaj   +1 more source

Updating Probabilities

open access: yesJournal of Artificial Intelligence Research, 2003
As examples such as the Monty Hall puzzle show, applying conditioning to update a probability distribution on a ``naive space'', which does not take into account the protocol used, can often lead to counterintuitive results. Here we examine why. A criterion known as CAR (``coarsening at random'') in the statistical literature characterizes when ...
Peter Grünwald, Joseph Y. Halpern
openaire   +7 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Prise de décision probabiliste spontanée chez les apprenants marocains

open access: yesAnnales de Didactique et de Sciences Cognitives
In our modern society, individuals are often faced with situations in which they have to make decisions spontaneously in an environment involving chance, in which the use of probability remains an adequate tool occupying an important status.
Zahid El M’Hamedi
doaj   +1 more source

Stabilisation of descriptor Markovian jump systems with partially unknown transition probabilities [PDF]

open access: yes, 2015
This paper is concerned with the stability and stabilisation problems for continuous-time descriptor Markovian jump systems with partially unknown transition probabilities.
Yan, Xinggang   +2 more
core   +1 more source

Juggling Probabilities

open access: yesThe American Mathematical Monthly, 2005
The act of a person juggling can be viewed as a Markov process if we assume that the juggler throws to random heights. I make this association for the simplest reasonable model of random juggling and compute the steady state probabilities in terms of the Stirling numbers of the second kind. I also explore several alternate models of juggling.
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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