Results 51 to 60 of about 545,514 (247)
Chances and risks in medical risk communication
GMS German Medical Science, 2015 Communication between physicians and patients in everyday life is marked by a number of disruptive factors. Apart from specific interests, mistakes, and misunderstandings on both sides, there are main factors that contribute to the risk in risk ...
Hoffrage, Ulrich, Koller, Michael
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Market-Implied Risk-Neutral Probabilities, Actual Probabilities, Credit Risk and News
IIMB Management Review, 2011 Motivated by the credit crisis, this paper investigates links between risk-neutral probabilities of default implied by markets (e.g. from yield spreads) and their actual counterparts (e.g. from ratings).
Shashidhar Murthy
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Viabilité, probabilités, induction
Tracés, 2013 While probability calculus helps favour the credence in a future occurrence, operational research prescribes a list of controls aimed at a given objective, generally in optimizing a given criterion.
Noël Bonneuil
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Liquefaction of Tangier soils by using physically based reliability analysis modelling
MATEC Web of Conferences, 2012 Approaches that are widely used to characterize propensity of soils to liquefaction are mainly of empirical type. The potential of liquefaction is assessed by using correlation formulas that are based on field tests such as the standard and the cone ...
Dubujet P. +3 more
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LPG–PCFG: An Improved Probabilistic Context- Free Grammar to Hit Low-Probability Passwords [PDF]
, 2022 Xiaozhou Guo +4 more
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Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Quantum Probabilities as Behavioral Probabilities
Entropy, 2017 We demonstrate that behavioral probabilities of human decision makers share many common features with quantum probabilities. This does not imply that humans are some quantum objects, but just shows that the mathematics of quantum theory is applicable to ...
Vyacheslav I. Yukalov, Didier Sornette
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