Results 121 to 130 of about 2,996,210 (293)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
The Holling Type II Population Model Subjected to Rapid Random Attacks of Predator
Journal of Applied Mathematics, 2018 We present the analysis of a mathematical model of the dynamics of interacting predator and prey populations with the Holling type random trophic function under the assumption of random time interval passage between predator attacks on prey. We propose a
Jevgeņijs Carkovs +2 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Positive Correlation between Normal Serum Gastrin Concentrations and Antral and Duodenal G Cells
Canadian Journal of Gastroenterology, 1994 It is controversial whether there is a correlation between serum gastrin concentrations and the density of G cells in the antral or duodenal mucosa. In this study, endoscopically obtained antral and duodenal biopsies were stained immunocytochemically for
WR Yacoub +4 more
doaj +1 more source
The Natural-Range Conception of Probability [PDF]
, 2009 Objective interpretations of probability are usually discussed in two varieties: frequency and propensity accounts. But there is a third, neglected possibility, namely, probabilities as deriving from ranges in suitably structured initial state spaces ...
Rosenthal, Jacob
core
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Basic elements and problems of probability theory [PDF]
, 1999 After a brief review of ontic and epistemic descriptions, and of subjective, logical and statistical interpretations of probability, we summarize the traditional axiomatization of calculus of probability in terms of Boolean algebras and its set ...
Primas, Hans, Hans Primas
core
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Forecast Encompassing Tests and Probability Forecasts [PDF]
We consider tests of forecast encompassing for probability forecasts, for both quadratic and logarithmic scoring rules. We propose test statistics for the null of forecast encompassing, present the limiting distributions of the test statistics, and ...
Harvey, David I, Clements, Michael P
core