Results 101 to 110 of about 7,822,373 (334)

Juggling Probabilities

open access: yesThe American Mathematical Monthly, 2005
The act of a person juggling can be viewed as a Markov process if we assume that the juggler throws to random heights. I make this association for the simplest reasonable model of random juggling and compute the steady state probabilities in terms of the Stirling numbers of the second kind. I also explore several alternate models of juggling.
openaire   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Mean Field Game with Delay: A Toy Model

open access: yesRisks, 2018
We study a toy model of linear-quadratic mean field game with delay. We “lift” the delayed dynamic into an infinite dimensional space, and recast the mean field game system which is made of a forward Kolmogorov equation and a backward ...
Jean-Pierre Fouque, Zhaoyu Zhang
doaj   +1 more source

Inverse Probability

open access: yesMathematical Proceedings of the Cambridge Philosophical Society, 1930
I know only one case in mathematics of a doctrine which has been accepted and developed by the most eminent men of their time, and is now perhaps accepted by men now living, which at the same time has appeared to a succession of sound writers to be fundamentally false and devoid of foundation.
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

On Drift Parameter Estimation in Models with Fractional Brownian Motion by Discrete Observations

open access: yesAustrian Journal of Statistics, 2014
We study a problem of an unknown drift parameter estimation in a stochastic differen- tial equation driven by fractional Brownian motion. We represent the likelihood ratio as a function of the observable process.
Yuliya Mishura, Kostiantyn Ralchenko
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

The Holling Type II Population Model Subjected to Rapid Random Attacks of Predator

open access: yesJournal of Applied Mathematics, 2018
We present the analysis of a mathematical model of the dynamics of interacting predator and prey populations with the Holling type random trophic function under the assumption of random time interval passage between predator attacks on prey. We propose a
Jevgeņijs Carkovs   +2 more
doaj   +1 more source

What probability probably isn't [PDF]

open access: yesAnalysis, 2014
Joyce and others have claimed that degrees of belief are estimates of truth-values and that the probability axioms are conditions of admissibility for these estimates with respect to a scoring rule penalising inaccuracy. In this paper I argue that the claim that the rules of probability are truth-directed in this way depends on an assumption which is ...
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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