Results 61 to 70 of about 384,626 (261)

On the distances between probability density functions

Electronic Journal of Probability, 2014
We give estimates of the distance between the densities of the laws of two functionals $F$ and $G$ on the Wiener space in terms of the Malliavin-Sobolev norm of $F-G.$ We actually consider a more general framework which allows one to treat with similar (Malliavin type) methods functionals of a Poisson point measure (solutions of jump type stochastic ...
Bally, V, CARAMELLINO, LUCIA
openaire   +5 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Properties of the integral curve and solving of non-autonomous system of ordinary differential equations

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2012
In this paper, we consider non-autonomous system of ordinary differential equations. For a given non-autonomous system, we introduce the distribution probability-density function of representative points of the ensemble of Gibbs, possessing all the ...
D. J. Kiselevich, G. A. Rudykh
doaj   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A comparative analysis of parametric survival models and machine learning methods in breast cancer prognosis

Scientific Reports
Accurate prediction of breast cancer survival is critical for optimizing treatment strategies and improving clinical outcomes. This study evaluated a combination of parametric statistical models and machine learning algorithms to identify the most ...
Sonia Kaindal, B. Venkataramana
doaj   +1 more source

Mean velocity and suspended sediment concentration profile model of turbulent shear flow with probability density function

Earth Sciences Research Journal, 2017
This work purposes a general mean velocity and a suspended sediment concentration (SSC) model to express distribution at every point of the cross section of turbulent shear flow by using a probability density function method.
Guanglin Wu, Liangsheng Zhu, Fangcheng Li   +2 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Estimate the probability density function of maximum temperature for the Middle East

Przegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2020
Pollution is one reasons for increase temperature which leads to increase the heat waves which have large socioeconomic and healthy impacts on Middle East.
Iqbal K. Al-Ataby, Amani I. Al-Tmimi
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source