Results 111 to 120 of about 9,281,981 (341)

Determination of Maximum Bayesian Entropy Probability Distribution [PDF]

Journal of Sciences, Islamic Republic of Iran, 2005
In this paper, we consider the determination methods of maximum entropy multivariate distributions with given prior under the constraints, that the marginal distributions or the marginals and covariance matrix are prescribed.
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

THE EFFECT OF ROUNDING ON THE PROBABILITY DISTRIBUTION OF REGRADING IN THE U.S. PEANUT INDUSTRY [PDF]

This article determines the effect of rounding (pointing-off) of grade percentages to the nearest whole number on the probability distribution of regrading in the peanut industry.
Richter, Francisca G.-C., Anderson, Kim B., Kenkel, Philip L., Diaz, Edgar F. Pebe, Brorsen, B. Wade   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Assessment of Riverine Currents to Estimate the Theoretical Hydrokinetic Power and Energy Using Hydraulic Geometry [PDF]

Journal of Agricultural Machinery
IntroductionThere are two types of hydropower harvesting methods: conventional and unconventional. In the conventional method, the potential energy of water is harvested using a dam or barrage. However, in the unconventional method, the kinetic energy of
M. Sadeghi-Delooee, R. Alimardani, H. Mousazadeh   +2 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Overcoming Dilution of Collision Probability in Satellite Conjunction Analysis via Confidence Distribution [PDF]

In satellite conjunction analysis, dilution of collision probability has been recognized as a significant deficiency of probabilistic inference. A recent study identified the false confidence problem as another limitation and suggested a possible causal ...
Hangbin Lee, Youngjo Lee
core   +1 more source

Supercanonical probability distributions

Physical Review E, 2018
The canonical probability distribution describes a system in thermal equilibrium with an infinite heat bath. When the bath is finite the distribution is modified. These modifications can be derived by truncating a Taylor-series expansion of the entropy of the heat bath, but their form depends on the expansion parameter chosen.
openaire   +4 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source