Results 41 to 50 of about 1,100,569 (292)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Analysis of Temperature and Thermal Stress for a Solar Power Tower Molten Salt Receiver under Multi-Source Uncertainties

open access: yesApplied Sciences, 2022
Although uncertainties such as solar radiation and material properties are generally involved in the solar receiver design process, current studies in the solar receiver field are based on deterministic models and do not incorporate these uncertainties ...
Yan Luo, Gen Li, Zhiyuan Wang, Tao Lu
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Conflations of probability distributions [PDF]

open access: yesTransactions of the American Mathematical Society, 2011
The conflation of a finite number of probability distributions P 1
openaire   +3 more sources

On φ-Families of Probability Distributions [PDF]

open access: yesJournal of Theoretical Probability, 2011
We generalize the exponential family of probability distributions. In our approach, the exponential function is replaced by a $φ$-function, resulting in a $φ$-family of probability distributions. We show how $φ$-families are constructed. In a $φ$-family, the analogue of the cumulant-generating function is a normalizing function.
Vigelis, Rui F., Cavalcante, Charles C.
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A Probability Distribution for Quantum Tunneling Times

open access: yesAdvances in High Energy Physics, 2018
We propose a general expression for the probability distribution of real-valued tunneling times of a localized particle, as measured by the Salecker-Wigner-Peres quantum clock.
José T. Lunardi, Luiz A. Manzoni
doaj   +1 more source

Probability distributions of frequency analysis of rainfall at the southwest region of Paraná State, Brazil

open access: yesRevista de Ciências Agroveterinárias, 2018
The study of monthly rainfall probabilities is of great importance due to the increasing occurrences of extreme events in different regions of Brazil. However, the rainfall distribution at the southwest region of Paraná State, Brazil, is still unknown ...
Frederico Márcio Corrêa Vieira   +3 more
doaj   +1 more source

Oil Spill SAR Image Segmentation via Probability Distribution Modeling

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2022
Segmentation of marine oil spills in synthetic aperture radar (SAR) images is a challenging task because of the complexity and irregularities in SAR images. In this work, we aim to develop an effective segmentation method which addresses marine oil spill
Fang Chen   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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