Results 121 to 130 of about 736,304 (285)
Advanced Science, EarlyView.Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao +18 more
wiley +1 more source
Improving How Microsoft Excel Displays Default Extremely Small Probability Values
Spreadsheets in Education, 2012 Microsoft Excel™’s default method of displaying probability values observed in the sample, in the case of very small values, is confusing to beginning students in statistics.
David A. Larson, Sylvia E. Rogers
doaj +2 more sources
Learned Conformational Space and Pharmacophore Into Molecular Foundational Model
Advanced Science, EarlyView.The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang +8 more
wiley +1 more source
SMEs probability of default: the case of the hospitality sector
Tourism & Management Studies, 2015 In this paper we analyze a set of financial ratios from hospitality sector SMEs in order to ascertain which factors determine a greater probability of default.
Luís Pacheco
doaj
The performance of credit rating systems in the assessment of collateral used in Eurosystem monetary policy operations [PDF]
The aims of this paper are twofold: first, we attempt to express the threshold of a single “A” rating as issued by major international rating agencies in terms of annualised probabilities of default.
Fernando Gonzáles +2 more
core
Advanced Science, EarlyView.This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang +10 more
wiley +1 more source
Advanced Science, EarlyView.The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou +5 more
wiley +1 more source
Credit ratings and credit risk [PDF]
This paper investigates the information in corporate credit ratings. We examine the extent to which firms' credit ratings measure raw probability of default as opposed to systematic risk of default, a firm's tendency to default in bad times. We find that
Jens Hilscher, Mungo Wilson
core
Advanced Science, EarlyView.This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li +12 more
wiley +1 more source
Is there Any Dependence Between Consumer Credit Line Utilization and Default Probability on a Term Loan? Evidence from Bank-Level Data [PDF]
Whereas recent studies on revolving lines of credit suggest a positive relationship between exposure at default and default probability on the line, this paper considers the relationship between two financial instruments through the simultaneous analysis
Anne-Sophie Bergerès +2 more
core