Results 131 to 140 of about 160,871 (306)

Screening Mortgage Default Risk: A Unified Theoretical Framework [PDF]

This study developed a unified framework for theoretically analyzing a set of mortgage attributes that screens borrower types according to their unobservable default risk.
Danny Ben-Shahar
core  

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Objective Bayesian Estimation of the Probability of Default

Journal of the Royal Statistical Society Series C: Applied Statistics, 2015
SummaryReliable estimation of the probability of default (PD) of a customer is one of the most important tasks in credit risk modelling for banks applying the internal ratings-based approach under the Basel II–III framework. Motivated by the desire to analyse reliably a low default portfolio of non-profit housing companies, we consider PD estimation ...
openaire   +1 more source

Applying default probabilities in an exponential barrier structural model [PDF]

This paper shows that the use of a time-dependant barrier in a structural model improve its flexibility because it allows to incorporate, as input, the probability of default. The main result achieved is the assessment that the default barrier is, indeed,
Enrico Moretto, Arianna Agosto
core  

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

Reducing Profit‐Seeking Default Behaviors in Demand Response via a Deep Learning‐Based Credit Scoring System

Engineering Reports
The participation of distributed energy resources in demand response enriches the manners of power grid dispatching. However, due to the profit‐seeking behaviors of some demand response suppliers, the cleared trading volumes may not be executed as ...
Ge Liu
doaj   +1 more source

Estimation of probability of default for low default portfolios

, 2022
Under Basel II, banks can use internal models to calculate their regulatory capital for credit risk, being the probability of default (PD) one of the fundamental parameters used in the quantification of credit risk. The Basel Committee on Banking Supervision requires financial institutions to incorporate a margin of conservatism to their estimates for ...
openaire   +1 more source

STAID: A Self‐Refining Deep Learning Framework for Spatial Cell‐Type Deconvolution with Biologically Informed Modeling

Advanced Science, EarlyView.
STAID is a unified deep learning framework that couples iterative pseudo‐spot refinement with neural network training through a feedback loop and exploits gene co‐expression information to model higher‐order interactions, achieving accurate and robust cell‐type deconvolution in spatial transcriptomics.
Jixin Liu, Shuli Sun, Zhengliang Lv, Xinyu Liu, Yihua Wang, Bingqiang Liu   +5 more
wiley   +1 more source

Implied Default Probabilities and Default Recovery Ratios: An Analysis of Argentine Eurobonds 2000-2002 [PDF]

This paper calculates implied recovery rates and implied default probabilities in a risk neutral setting for Argentine US-Dollar Eurobonds during the Argentine crisis from 2000 to 2002.
Jochen R. Andritzky
core  

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source