Results 61 to 70 of about 600,202 (264)
Probability Inequalities and Errors in Classification
The Annals of Statistics, 1974 Let $X$ and $Y$ be two $p \times 1$ random vectors distributed according to a normal distribution with respective mean vectors $\mu$ and $a\mu$ and covariance matrix $\begin{pmatrix}I_p & \rho I_p \\ \rho I_p & I_p\end{pmatrix}.$ Let $S$ be a random $p \times p$ matrix distributed as the Wishart distribution $W_p(I_p, r)$, independently of $X$ and $Y$.
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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Searching with known error probability
Theoretical Computer Science, 1989 We study the problem of interactive searching in a set of numbers using comparison queries, under the assumption that each answer can be erroneous with a constant probability p and that a given reliability ...
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
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Micro-Diversity Analysis of Error Probability and Channel Capacity over Hoyt-Gamma Fading [PDF]
Radioengineering, 2017 In wireless communication system, various parameters such as average symbol/bit error probability (ASEP/ABEP), outage probability and average channel capacity, etc. are studied for its performance analysis. In this paper, the performance of L-Hoyt/Gamma (
S. Kumar, S. K. Soni, P. Jain
doaj
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
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FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
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