Results 61 to 70 of about 423,933 (267)
Weibull Failure Probability Estimation Based on Zero-Failure Data [PDF]
Mathematical Problems in Engineering, 2015 Reliability testing is often carried out with small sample sizes and short duration because of increasing costs and the restriction of development time. Therefore, for highly reliable products, zero-failure data are often collected in such tests, which could not be used to evaluate reliability by traditional methods.
Jiang, Ping +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
ModellingBased on the solutions of deterministic fracture mechanics and the methods of probability theory, the algorithm for calculating the probabilistic strength characteristics of plate elements of structures with an arbitrary stochastic distribution of ...
Roman Kvit +3 more
doaj +1 more source
A Holistic Approach to Risk-Based Maintenance Scheduling for HV Cables
IEEE Access, 2019 Regular maintenance inspection and testing is essential in extending cable life and reducing failure probability. This can be achieved by improving the conduit conditions and taking corrective actions on faulty cable components and accessories ...
Yanqun Liao +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
بهداشت کار و ارتقای سلامت, 2020 Introduction: To prevent accidents and minimize the risk of unexpected disasters in the oil, gas, and petrochemical industries, an inspection of equipment in terms of mechanical integrity and safe and consistent service providing are of utmost importance.
Amir BARKHORDARI +4 more
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