Results 71 to 80 of about 12,206,178 (323)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Inundation Risk Assessment of Underground Space Using Consequence-Probability Matrix

open access: yesApplied Sciences, 2019
Increases in the frequency and severity of extreme rainfall might cause catastrophic submergence of underground spaces. Therefore, it is essential to predict the flood risk for proactive design. This study presents the methodology of acquiring risk level
Yong-sik Han   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

On the completeness of the universal knowledge-belief space [PDF]

open access: yes, 2011
Meier (2008) shows that the universal knowledge-belief space exists. However, besides the universality there is an other important property might be imposed on knowledge-belief spaces, inherited also from type spaces, the completeness.
Pintér, Miklós
core   +1 more source

The probability of non-confluent systems [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
We show how to provide a structure of probability space to the set of execution traces on a non-confluent abstract rewrite system, by defining a variant of a Lebesgue measure on the space of traces.
Alejandro Díaz-Caro, Gilles Dowek
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Quantum Knowledge in Phase Space

open access: yesEntropy, 2023
Quantum physics through the lens of Bayesian statistics considers probability to be a degree of belief and subjective. A Bayesian derivation of the probability density function in phase space is presented.
Davi Geiger
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Generating Synthetic Space Allocation Probability Layouts Based on Trained Conditional-GANs

open access: yesApplied Artificial Intelligence, 2019
In this paper, a data-driven generative method is applied to generate synthetic space allocation probability layout. This generated layout could be helpful in the early stage of an architectural design.
Morteza Rahbar   +4 more
doaj   +1 more source

Fuzzy Probability Spaces and Their Applications in Decision Making

open access: yesAustrian Journal of Statistics, 2016
In this paper, two types of fuzzy probability spaces will be introduced and their applications in methods of decision making under risk (especially in the Decision Matrix Method) will be described.
Jana Talašová, Ondřej Pavlačka
doaj   +1 more source

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