Results 61 to 70 of about 2,506,239 (282)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Existence and uniqueness of mild solution to fractional stochastic heat equation

Modern Stochastics: Theory and Applications, 2018
For a class of non-autonomous parabolic stochastic partial differential equations defined on a bounded open subset $D\subset {\mathbb{R}^{d}}$ and driven by an ${L^{2}}(D)$-valued fractional Brownian motion with the Hurst index $H>1/2$, a new result on ...
Kostiantyn Ralchenko, Georgiy Shevchenko
doaj   +1 more source

Discovery of miR-mRNA interactions via simultaneous Bayesian inference of gene networks and clusters using sequence-based predictions and expression data

Journal of Integrative Bioinformatics, 2013
MicroRNAs (miRs) are known to interfere with mRNA expression, and much work has been put into predicting and inferring miR-mRNA interactions. Both sequence-based interaction predictions as well as interaction inference based on expression data have been ...
Godsey Brian
doaj   +2 more sources

Quasi-probability representations of quantum theory with applications to quantum information science

, 2011
This article comprises a review of both the quasi-probability representations of infinite-dimensional quantum theory (including the Wigner function) and the more recently defined quasi-probability representations of finite-dimensional quantum theory.
Alicki R, Alicki R, Beltrametti E G, Bohm D, Cereceda J L, Chaturvedi S, Christensen O, Christopher Ferrie, Cohendet O, Cohendet O, Combescure M, Datta A, Ferrie C, Ferrie C, Feynman R P, Franco R, Fuchs C A, Fuchs C A, Fuchs C A Schack R, Giraud O Braun P A Braun D, Gottesman D, Hakioglu T, Hardy L, Hardy L, Harrigan N Rudolph T, Husimi K, Isham C, Ivonovic I D, Joos E, Kalmykov Y P, Kenfack A, Kochen S, Laflamme R, Livine E R, Luis A, Mandel L, Mari A Kieling K Nielsen B M Polzik E S Eisert J, Morris R, Nielsen M A, Porta Mana P G L, Porta Mana P G L, Porta Mana P G L, Redhead M, Ruzzi M, Schack R, Scott A J, Shepherd D, Shor P W, Stratonovich R L, Vourdas A, Walls D F, Zauner G, Zueco D   +52 more
core   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Maximum likelihood estimation in the non-ergodic fractional Vasicek model

Modern Stochastics: Theory and Applications, 2019
We investigate the fractional Vasicek model described by the stochastic differential equation $d{X_{t}}=(\alpha -\beta {X_{t}})\hspace{0.1667em}dt+\gamma \hspace{0.1667em}d{B_{t}^{H}}$, ${X_{0}}={x_{0}}$, driven by the fractional Brownian motion ${B^{H}}$
Stanislav Lohvinenko, Kostiantyn Ralchenko   +1 more
doaj   +1 more source

Quantum mechanics as a theory of probability [PDF]

, 2005
We develop and defend the thesis that the Hilbert space formalism of quantum mechanics is a new theory of probability. The theory, like its classical counterpart, consists of an algebra of events, and the probability measures defined on it.
Pitowsky, Itamar
core   +4 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Performance-Utilization Trade-Offs for State Update Services in 5G NR Systems

IEEE Access
State update applications reporting the state of a remote system to the control center constitute a critical part of modern Internet of Things (IoT) applications.
Ekaterina Markova, Varvara E. Manaeva, Elena Zhbankova, Dmitri Moltchanov, Pavel Balabanov, Yevgeni Koucheryavy, Yuliya Gaidamaka   +6 more
doaj   +1 more source

To save or not to save your family member’s life? Evolutionary stability of self-sacrificing life history strategy in monogamous sexual populations

BMC Evolutionary Biology, 2019
Background For the understanding of human nature, the evolutionary roots of human moral behaviour are a key precondition. Our question is as follows: Can the altruistic moral rule “Risk your life to save your family members, if you want them to save your
József Garay, Barnabás M. Garay, Zoltán Varga, Villő Csiszár, Tamás F. Móri   +4 more
doaj   +1 more source