Results 41 to 50 of about 1,248,041 (248)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Cognitive biases as Bayesian probability weighting in context

Frontiers in Psychology
IntroductionHumans often exhibit systematic biases in judgments under uncertainty, such as conservatism bias and base-rate neglect. This study investigates the context dependence of these biases within a Bayesian framework.MethodsForty-eight participants
Bruno Kopp
doaj   +1 more source

Propensity Score Methods in Rhinologic Observational Research: Principles, Applications, Extensions, and Practical Considerations [PDF]

Journal of Rhinology
Randomized controlled trials (RCTs) remain the gold standard for evaluating treatment efficacy because randomization minimizes measured and unmeasured confounding.
Jae Hoon Cho
doaj   +1 more source

Inverse-probability weighting and multiple imputation for evaluating selection bias in the estimation of childhood obesity prevalence using data from electronic health records

BMC Medical Informatics and Decision Making, 2020
Background and objectives Height and weight data from electronic health records are increasingly being used to estimate the prevalence of childhood obesity.
Carmen Sayon-Orea, Conchi Moreno-Iribas, Josu Delfrade, Manuela Sanchez-Echenique, Pilar Amiano, Eva Ardanaz, Javier Gorricho, Garbiñe Basterra, Marian Nuin, Marcela Guevara   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Probabilities as Similarity-Weighted Frequencies [PDF]

Econometrica, 2005
A decision maker is asked to express her beliefs by assigning probabilities to certain possible states. We focus on the relationship between her database and her beliefs. We show that if beliefs given a union of two databases are a convex combination of beliefs given each of the databases, the belief formation process follows a simple formula: beliefs ...
Gilboa, Itzhak, Billot, Antoine, Samet, Dov, Schmeidler, David   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Inverse Probability Weighting Enhances Absolute Risk Estimation in Three Common Study Designs of Nosocomial Infections

Clinical Epidemiology, 2022
Paulina Staus,1 Maja von Cube,1,* Derek Hazard,1,* Sam Doerken,1 Ksenia Ershova,2 James Balmford1 ,† Martin Wolkewitz1 1Institute of Medical Biometry and Statistics, Division Methods in Clinical Epidemiology, Faculty of Medicine and Medical ...
Staus P, von Cube M, Hazard D, Doerken S, Ershova K, Balmford J, Wolkewitz M   +6 more
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