Results 71 to 80 of about 741,544 (321)

Doubly robust estimators for generalizing treatment effects on survival outcomes from randomized controlled trials to a target population

Journal of Causal Inference, 2022
In the presence of heterogeneity between the randomized controlled trial (RCT) participants and the target population, evaluating the treatment effect solely based on the RCT often leads to biased quantification of the real-world treatment effect.
Lee Dasom, Yang Shu, Wang Xiaofei
doaj   +1 more source

Foundations of the Rank-Dependent Probability Weighting Function [PDF]

SSRN Electronic Journal, 2019
The psychological basis for rank-dependent probability weighting, and for an inverse-S probability weighting function (PWF) in particular, has often been questioned. I examine the existence and shape of the PWF in a model allowing for optimism/pessimism over probability distributions and for loss averse/gain loving stochastic reference dependence.
openaire   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Study on VLC Channel Modeling Under Random Shadowing

IEEE Photonics Journal, 2017
Recently, visible light communication (VLC) based on LEDs has attracted much attention. In order to realize multiusers indoor VLC systems, a reasonable channel model considering random shadowing, which is first proposed to the best of our knowledge, is ...
Zanyang Dong, Tao Shang, Yan Gao, Qian Li   +3 more
doaj   +1 more source

Risk-taking in disorders of natural and drug rewards: neural correlates and effects of probability, valence, and magnitude. [PDF]

, 2014
Pathological behaviors toward drugs and food rewards have underlying commonalities. Risk-taking has a fourfold pattern varying as a function of probability and valence leading to the nonlinearity of probability weighting with overweighting of small ...
A Muller, A Rangel, A Schafer, AJ Lawrence, AM Morales, AP Le Berre, Brian L Odlaug, C Trepel, Christian Ruck, D Kahneman, D Prelec, DJ Levy, Edward T Bullmore, GF Koob, GJ Wang, H Nakama, H Takahashi, H Ziauddeen, J Svaldi, J Tanabe, Jon E Grant, Jonathan Wood, Katherine Derbyshire, Laurel S Morris, Liana RN Schreiber, LK Fellows, Michael A Irvine, MP Paulus, Neil A Harrison, NM Avena, R Pignatti, RD Rogers, RZ Goldstein, RZ Goldstein, SM Tom, SR Chamberlain, T Insel, TR Franklin, Trevor W Robbins, UN Danner, V Voon, V Voon, Valerie Voon, Vladan Rankov, Yulia Worbe   +44 more
core   +3 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Nonparametric probability weighted empirical characteristic function and applications

Statistics & Probability Letters, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Meintanis, S.G., Ushakov, N.G.
openaire   +4 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Star-shaped probability weighting functions and overbidding in first-price auctions [PDF]

Economics Letters, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Armantier, Olivier, Treich, Nicolas
openaire   +5 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source