Results 241 to 250 of about 229,699 (289)

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

Advanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia, Lei Liu, Shuang Jin, Guangxu Fang, Chang Yu, Yunyun Wu, Lunli Xiang, Hongrui Zhu, Zhenqiang Wang, Jixi Zhang   +9 more
wiley   +1 more source

Barriers and facilitators to the use of Hypercare APK app in hypertension management: a qualitative inquiry into highly educated participants' experiences in Ilorin, Nigeria. [PDF]

Front Digit Health
Yakubu MO, Esan DT.
europepmc   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Qualitative study on nurse preceptors' preparedness, roles and familiarity with the basic principles of teaching and learning in a district hospital in Ghana. [PDF]

BMJ Open
Boakye DS, Amoah VMK, Boateng EA, Antwi J, Yeboah J, Owusu J.   +5 more
europepmc   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source

Salivary Titanium Level as a Non-invasive Biomarker for Peri-Implantitis: A Prospective Study. [PDF]

Cureus
Sharma K, Swati S, Jamil P, Challa RSP, Ambata N, Tiwari RV, Sharma M, Dixit H.   +7 more
europepmc   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Short-Term Feeding Disruption Effects and Efficacy of Six Biopesticides Against <i>Empoasca onukii</i> (Hemiptera: Cicadellidae). [PDF]

Biology (Basel)
Jia Z, Yang C, Liu Y, Yang Y, Zhou R, Cheng Z, Geng S, Xu Y, Chen Z, Qiao L.   +9 more
europepmc   +1 more source

Metastatic Lung Carcinoma Presenting as Pyogenic Granuloma Around Dental Implant. [PDF]

Clin Case Rep
Gidici S, Akçiçek G, Boyacıoğlu Erden H.   +2 more
europepmc   +1 more source

Evaluation of the performance of an artificial intelligence model in recognizing the habitual mixed language in Taiwan for generating periodontal charting text reports. [PDF]

J Dent Sci
Lo YJ, Chang YC, Chen CH, Wang HP, Wang HC, Ohiro Y, Fang CY.   +6 more
europepmc   +1 more source