Results 141 to 150 of about 89,379 (230)

Convergent evolution of metabolic functions: Evidence from the gut microbiomes of humans and dogs

open access: yesiMetaOmics, EarlyView.
Dogs have undergone convergent evolution in their genome with humans in long‐term co‐living. Studies have shown that the gut microbiomes of dogs exhibit greater similarity to those of humans compared to mice and pigs. In our study, we first compared the gut microbiomes of macaques, three dog groups, and two wolf groups to those in humans.
Xiaoyang Wang   +10 more
wiley   +1 more source

<i>Bifidobacterium</i> supplementation maintains gut microbiota stability and enhances well-being during short-term travel. [PDF]

open access: yesFront Nutr
Wang L   +11 more
europepmc   +1 more source

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

open access: yesiMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang   +7 more
wiley   +1 more source

Precise probiotic therapy: Advances, bottlenecks, and the road to microbiome-informed nutrition. [PDF]

open access: yesGut Microbes
Jiang Y   +6 more
europepmc   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

open access: yesiMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Early-life maternal probiotic supplementation programs sex- and region-specific gene expression in the adult offspring brain. [PDF]

open access: yesBrain Behav Immun Health
Siegler Lathrop T   +3 more
europepmc   +1 more source

The gut microbiome promotes the growth performance of black soldier fly larvae by detoxifying uric acid

open access: yesiMetaOmics, EarlyView.
This study demonstrates the detrimental effects of exogenous uric acid (UA) on the growth of black soldier fly (BSF) larvae, highlighting the role of gut microbiota in UA degradation. We isolated UA‐degrading bacterial strains associated with BSF, including Enterococcus faecalis AHAU24.
Xiaowen Ji   +12 more
wiley   +1 more source

Probiotic Supplementation Reduces RRTIs and Enhances Gut Microbial and Immunity in Children: A Randomized Controlled Trial. [PDF]

open access: yesJ Microbiol Biotechnol
Chen K   +10 more
europepmc   +1 more source

Ribosomal RNA operon copy number: A trait‐informed framework to close the microbial cultivation gap

open access: yesiMetaOmics, EarlyView.
The vast majority of microbes remain uncultured, constraining functional validation and limiting microbiome‐based applications. We show that ribosomal RNA operon (rrn) copy number—a stable, phylogenetically conserved genomic trait—is strongly correlated with cultivation outcomes across ecosystems.
Yuxiao Huang   +8 more
wiley   +1 more source

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