Results 71 to 80 of about 16,543,141 (273)
Possibilities of geographic information system in solution making of the Sjenica's commune development [PDF]
The paper describes reality method sand geographical information systems (GIS- technologies) in integration GIS system. Sjenica is a specific area of the our state and therefore must notes of all elements and factors in environmental.
Šabić Dejan, Milanović Miško
doaj +1 more source
The Effect of Problem Based Learning Model on Critical Thinking Skills in the Context of Chemical Reaction Rate [PDF]
The previous research result showed that the learning model based on the investigation could increase the students' critical thinking skills. The aim of this research was to measure the effectiveness of the using of problem-based learning model to ...
Dakabesi, D. -. (Daud) +1 more
core
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Re-Thinking the “Problem” in Inquiry-Based Pedagogies through Exemplarity and World-Oriented
This paper conducts a theoretical exploration of the inquiry-problem in problem-oriented pedagogies. Specifically, the article draws on a critical reflection of the addition of a global and internationalisation dimension to the problem-oriented project ...
Simon Warren
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
The article presents several mathematical problems concerning Euclidean ...
Yevdokimov, Oleksiy
core
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
PATRIOTISM AS А VALUE: ESSENCE AND FUTURE PROSPECTS
The article is devoted to the problem of patriotism based on the unity of its cognitive and emotional components. Therefore, patriotism as a social phenomenon has been characterized.
Ivan Bekh
doaj +1 more source

