Results 71 to 80 of about 16,498,200 (273)
Variants of the Busemann-Petty problem and of the Shephard problem
, 2016 We provide an affirmative answer to a variant of the Busemann-Petty problem, proposed by V.~Milman: Let $K$ be a convex body in ${\mathbb R}^n$ and let $D$ be a compact subset of ${\mathbb R}^n$ such that, for some $1\ls k\ls n-1$, $$|P_F(K)|\ls |D\cap F|
Giannopoulos, Apostolos +1 more
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
, 2009 The article presents several mathematical problems concerning Euclidean ...
Yevdokimov, Oleksiy
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Academic citizenship: A radical practice perspective
JPHEThis article presents how we might think about academic citizenship through a radical practice perspective. The assumption is that academics, alongside other actors, enact the university in their everyday practices.
Eva Bendix Petersen
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
PATRIOTISM AS А VALUE: ESSENCE AND FUTURE PROSPECTS
Education: Modern Discourses, 2018 The article is devoted to the problem of patriotism based on the unity of its cognitive and emotional components. Therefore, patriotism as a social phenomenon has been characterized.
Ivan Bekh
doaj +1 more source
Solved! Making the case for collaborative problem-solving [PDF]
, 2017 This report argues that the ability to solve problems with others is a crucial skill for our young people in the workplace of the future but the current education system does little to support it.
Baines, Ed +4 more
core +1 more source