In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu +16 more
wiley +1 more source
The COLIEE 2025 Competition on Legal Information Extraction and Entailment: Overview, Discussion, and Dataset Expansion. [PDF]
Goebel R +7 more
europepmc +1 more source
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich +2 more
wiley +1 more source
A Meta-Analysis of Mathematics Fact Fluency Interventions for Students With Mathematics Difficulties (MD). [PDF]
Douglas GP +4 more
europepmc +1 more source
Consensus Formation and Change are Enhanced by Neutrality
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag +3 more
wiley +1 more source
Comprehension strategy instruction for Hispanic children with mathematical learning difficulties. [PDF]
Orosco MJ, Mamedova S, Abdulrahim NA.
europepmc +1 more source
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch +4 more
wiley +1 more source
Developing a multidimensional pedagogical framework for safety education in early childhood: mapping systematic review insights to <i>Sheriff Labrador</i>. [PDF]
Lasekan OA, Pena MTG, Mathew BS.
europepmc +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
Impact of Generative AI-assisted programming on the computational thinking of high school students. [PDF]
Guo R, Li G, Miao H, Pi Z, Xie L.
europepmc +1 more source

