Results 71 to 80 of about 1,027,084 (263)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Analysis of Problem of Perceiving and Understanding Literary Texts by Philology Students
Психолінгвістика, 2019 Introduction. The article discloses the importance of conducting psycholinguistic analysis of perceiving and understanding voluminous literary texts by philology students; the issue is relevant as there is a lack of research that concerns revealing the ...
Інна Хижняк +1 more
doaj +1 more source
Understanding Understanding and Non-Understanding: The Problems and Possibilities
, 2021 Life is not limited to the coordinated functioning of millions of cells that make an individual or to one’s struggle for survival. It’s also about our pursuit to reach the Ultimate, or the Absolute in Hegel’s terms. In his search for the absolute, he too yearned for someone who would truly understand him.
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Understanding the Problem of Practice: An Analysis of Professional Practice EdD Dissertations
Impacting Education, 2018 Investigating a “problem of practice” is a signature feature of the EdD dissertation. Yet, little is known about how doctoral students derive their problems, the nature of the problems they study, and the impact studying problems of practice has on ...
Vera Wei Ma +3 more
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UNDERSTANDING ARITHMETIC PROBLEMS IN TURKISH [PDF]
International Journal of Pattern Recognition and Artificial Intelligence, 2001 This paper describes ALİ, the first computer program which can solve primary school-level arithmetic problems stated in Turkish. This task involves several subtasks: morphological analysis of every word in the input, syntactic analysis of each sentence, semantic analysis of words, providing a description of the commonsense world that is large enough ...
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Political development of Kosovo-Metohian problem [PDF]
Baština, 2013 This issue represents one of the urgent international problems. Processes which are the study subject of the political development of Kosovo-Metohian problem have not finished yet, so that there is not enough original material.
Vujović Ognjen
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source