Results 41 to 50 of about 7,778,579 (239)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

INFLUENCE OF PROBLEM POSING METHOD ON PROBLEM SOLVING SKILLS

open access: yesJurnal Pendidikan Ilmu Sosial, 2018
This study aims to analyze the difference between problem-solving ability using problem posing method and conventional method. This research was conducted at SMAN 1 Parongpong Kabupaten Bandung Barat. The research subjects were students of class X Social
Dewi Daryati
doaj   +1 more source

MENINGKATKAN KEMAMPUAN PEMECAHAN MASALAH SISWA MELALUI PENDEKATAN REALISTIC MATHEMATICS EDUCATION

open access: yesAksioma: Jurnal Program Studi Pendidikan Matematika, 2022
Mastering problem-solving skills is important for students in the 21st century. The RME approach can be an alternative to improve students' problem-solving skills.
Zulfan Hanif Rahman, Reni Setyaningsih
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Skills for Life Series: Problem-Solving [PDF]

open access: yes
Problem-solving skills help individuals cope with problem by analyzing it, and proposing viable solutions based upon available information. They are crucial for learning, societal participation, and personal activities, as well as for employment success.
Inter-American Development Bank
core   +1 more source

Analysis of Programming Skills Concept in Developing Problem Solving Skills

open access: yesJurnal Pendidikan Teknologi dan Kejuruan, 2019
Programming refers to a set of processes of writing, testing and correcting the program code aimed at creating a program that can do certain works in accordance with the programmer’s instructions, it requires the mastery of algorithms, logic and ...
Rina Harimurti   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Keterampilan Pemecahan Masalah Mahasiswa Dalam Pembelajaran Bandul Fisis Menggunakan Model Problem Solving Virtual Laboratory

open access: yesJPFT (Jurnal Pendidikan Fisika dan Teknologi), 2017
This study aims to explore pre-service physics teachers’ problem-solving skills through the implementation of problem solving virtual laboratory (PSVL) model on the concept of simple pendulum.
Sutarno Sutarno   +4 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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